I'm going with Declaration of Independence author Thomas Jefferson. If British when he started, American when he finished.
If the 'most influential American writer' means 'the one most important to the US becoming its own country', then the answer is Thomas Paine. His American Crisis papers buttressed the flagging revolutionary movement and made the common folk actually care. Before Paine's propaganda, the majority of colonists saw themselves as British subjects and the fight for independence was only really supported by the landed gentry.
The American Crisis papers made the common folk care, and without them there likely isn't enough popular support to win the war.
Paine > Jefferson as pertains to the American cause (and Paine > Jefferson as person).
Just then Tom Paine, himself
Came running from across the field
Shouting at this lovely girl
And commanding her to yield
And as she was letting go her grip
Up Tom Paine did run
"I'm sorry, sir", he said to me
"I'm sorry for what she's done"