social justice issues. I'm waiting for a computational model of government so we can question and improve these models without violence. It seems that (in America at least) politics is so tightly woven into a person's identity that to question their political beliefs offends them personally. Thus we languish without being able to critically think of better forms of government/politics.
Also mental health issues (which is closely related to human rights issues). After watching Medicating Normal, I've lost hope in the psychiatric/pharmaceutical system. Why are there no better solutions to depression? It seems to be affecting a large number of people.