These wide-gamut monitors have both a deeper red source (longer wavelength) and a deeper green (shorter). So the red and green peaks are quite a bit farther apart -- possibly as much as 80% -- than they are with a standard CCFL or WLED backlight. Combine that with high-index plastic lenses, which have higher dispersion (a measure of chromatic aberration) the higher their refractive index, and you can get a real problem.
Since my correction is about -6.75 diopters, and I have wide-gamut monitors, I had a pair of glasses made with CR-39, a relatively low-index plastic with low dispersion, almost as low as that of glass. CR-39 is generally not used for such strong lenses because they would need to be thick at the edges, but this problem can be minimized by making the lens round in shape and not too large.