What to do? Take your skills and put them into your own startup. I rolled with the times, hedged my bets and invested my life savings, as documented here:
https://news.ycombinator.com/item?id=22958528 https://news.ycombinator.com/item?id=22970810
(The only thing I'd amend my 4-month old comments with, is, chill out! The daily ups and downs are not important compared to the Fed Put. And, long-term, watch out for the ultimate decline of the dollar, the shift from fiat to bitcoin. Palihapitiya has sage advice in keeping at least 1% of your net worth in bitcoin.)
Investing well is a mindset, and the essential thing to do is focus on your methodology, and your connection to the world around you. There is no substitute for critical, rational, non-cynical thinking.