(I have never even seen one, but I've seen strong online recommendations for them from people who can only use one arm.)
Another option would be left/right handed Dvorak, which is built-in on many OSs, or any other single-handed layout on a programmable keyboard.
https://www.maltron.com/store/p19/Maltron_Single_Hand_Keyboa...
I’m looking for something cheaper and smaller that can be used easily for setting up new machines etc. without needing to lug around a huge device.
If I lost the use of one hand, I'd modify one of the ergonomic open source keyboards to have an eighth column, and... well, ask someone to make it for me. (One handed soldering? No...) I'd then set the Dvorak one-handed layout, which has 8 columns of letters, plus more of punctuation and numbers. The extra keys would be accessed by first pressing a modifier thumb-key, or by activating the "Caps" Lock for the number/punctuation layer.
Alternatively, I might stick with one of the existing designs (Diverge 4?) and move the Q, Z and X keys onto the secondary layer. (Though I would keep Z if my name were Zepto.)
With a keyboard running QMK[3], you can essentially program it however you like. A "Shift" key can be sticky (press shift, then the letter). A modifier key can select a different layer of keys, e.g. numbers and punctuation. A different modifier key could be a lock for that layer.
Pressing two adjacent keys simultaneously (e.g. JK on a Qwerty board) could be "enter" or "space". Or if there are keys it is practical to hold down, you can change the function depending whether it's held down or pressed (e.g. Enter or Ctrl).
Here's one possibility using the Diverge 4 right half: http://www.keyboard-layout-editor.com/#/gists/5ebe720a10b353...
[1] http://xahlee.info/kbd/diy_keyboards_index.html "Ergodox variations" (some are available preassembled)
However, that might not be a great idea. Some two-handed keyboard reviewers have tried it out and at least one of them thinks its an absolutely horrifying device that he can't imagine anyone learning to type well on. He seemed to think it developed a reputation as being a good one handed computer simply because there aren't any other options.
People have had some reliability issues though, so it's a mixed bag. They have recently gotten some new tooling, so hopefully they will start making keyboards that look somewhat not like a shit 90s keyboard.
I am more interested in the newest addition to the unicomp portfolio. The "new model m" and their upcoming TKL boards seem like something I will like :)