If your threat model includes your ISP, but does not extend to nation-state level adversaries, then a good private VPN should be a decent enough solution, although a public VPN might be easier and still adequate.
Source: I personally pissed off the Director of the NSA in November of 1992 (see http://www.shub-internet.org/brad/cacm92nov.html ). At the time, my clearance was Top Secret/SCI, and I had been read onto multiple compartments — including the ones for ECHELON, KEYHOLE, etc.... So far as I know, I am still on their shit list, albeit not as high as Snowden or Binney.
So the best bet is staying off the shit lists of the NSA and other global adversaries.
However, I have used personal VPNs tunneled through Tor. But I was very careful to be anonymous about the VPS I used. And it was just to get around blocking of Tor exits.