That’s one of the biggest improvements in quality of life when I work remotely. I find working in an office (especially open space or cubes) very exhausting due to noise and lack of privacy. So I come home at night totally exhausted and do nothing. When I work from home I naturally feel motivated to do something after work which I find very positive.
But, and this can be hard for people, you have to make an effort to be social. The default that someone works with you they will likely have to talk to you is no longer an option.
I need socialization at least once/week or I start getting depressed.
I'm into music, so I joined our local community choir. It's not necessarily the style of music I listen to on my own or like to play/perform (I'm more into guitar and folk music), but its a very social activity that gets me out of the house once a week, with people that I have some things in common. I've made some great friends and got to know a lot of people in my community that I would not have otherwise.
I really start to miss it when we're off-season (long summer break), because of that feeling you get when you haven't left the house for a week or so. :)
Becoming remote didn't change that. But traveling while being remote did. It's hard not to walk into great wall of socializing to balance out all the abstract work we do day today.
Personally, I kicked started it by putting all my stuff in storage. I also started slowly by traveling within the US and moving month to month. My boss does it cool, important to note that not all remote work environments will be okay with you traveling.