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Eventually, you'd mount the laser on the drone, and let it wander around the city doing a search.

The targeting laser tells you, "yes, this is your target," and you just continue painting them with it until they die.

100% success, expected time until death 3-70 years with a 95% confidence interval

High power lasers aren't easy at all to create and point. A bomb or gun is much easier.

I think OP was alluding to a rifle with a laser sight

? OP is saying that the laser will identify the target, the weapon will 'take out' the target.