I agree that a virtual 32 bit distro is probably the only way this makes sense. I can't imagine that a project like wine has any capacity to do all the security updates and dealing with all of multi distro complexities to work around the fact that they could have wildly different library sets to stand on. It could potentially be done as part of a distro package for Ubuntu but it would be a single person replicating the effort of the core libs for ubuntu over again, just for this one corner project.

Either that or someone's going to have to rebuild WOW64 on top of wine? I guess that could happen.