It seems to me, we'll probably wind up with a base linux container for 32-bit wine support... now, what that is based on, and how well it's maintained is another issue entirely.

By comparison there's DosEMU, DosBox and others for DOS, but Windows/Wine is a much larger surface. I can only hope there's enough community to create effectively a "virtual distro base" that's 32-bit so that said apps can continue to run.

Should be fairly similar to the effort on windows for WSL2 ... Would be interesting to see MS take a similar approach for DOS/Win32 support. Given the changes in MS, would actually be VERY interesting to see MS support Wine32 under WSL2 so that they could remove the 32bit support from windows as well. Unlikely, but one can dream.