@ASmallFiction had a beautiful, succinct take on this recently:
"Are we alone in the universe?" she asked.
"Yes," said the Oracle.
"So there's no other life out there?"
"There is. They're alone too."
"Are we alone in the universe?" she asked.
"Yes," said the Oracle.
"So there's no other life out there?"
"There is. They're alone too."
I'd say there certainly is life out in the Universse and it's quite possible there is intelligent life.
But the distances are so large that we will never meet any other intelligent life before our own civilization vanishes.
The evidence becomes more and more every day that life is not a one in a trillion miracle but a natural product of certain environments. To assume we will never have contact with other lifeforms seems like a huge jump.