Major doesn't seem herself. she seems confused, and weak. the real Major we know is straight badass, with some natural, intelligent introspection that would come from being a full-body cyborg.
I don't like what they've done to the flesh. she should appear more anatomically human, without breaks in the flesh, with nipples, etc. it adds more to Major being comfortable with herself. this is minor in the scheme of things, I suppose. but it is quite a big decision to make, and if they didn't see this through correctly, it makes me wonder about the rest of the film.
and as someone pointed out, when an official trailer[1] opens up with the main actor saying how much they enjoyed making the movie, that's never a good sign.