Well... I don't know... There isn't much in this trailer... Can be a good movie, but I don't bet on it.
I don't like what they've done to the flesh. she should appear more anatomically human, without breaks in the flesh, with nipples, etc. it adds more to Major being comfortable with herself. this is minor in the scheme of things, I suppose. but it is quite a big decision to make, and if they didn't see this through correctly, it makes me wonder about the rest of the film.
and as someone pointed out, when an official trailer[1] opens up with the main actor saying how much they enjoyed making the movie, that's never a good sign.
If you've seen the recent OVAs (GitS Arise) this could be an alternate view of what 'the major' looked like before she became the team lead we're more familiar with in other movies and series from this fictional universe. In a time when she is still a slave of 'the system' (I mean that more in the military/industrial/political greed context).
Having made that speculation, I'm not sure that's where this movie actually is. I hope the trailer is simply trying to convey the genera, art-styles, and beginning of the plot (without too many spoilers); but I'm used to trailers that pretty much spoil everything except the culmination of the film.
In USA animations aim for G and PG... so not so bad as possible...