Then you're not writing JavaScript, which was OP's concern. TypeScript is fine (although Elm, Swift, and Haskell are more interesting, IMO).
Compilation phase removes the annotations, after that point it is pure JavaScript.
How are Swift and Haskell relevant for client side web development?
Edit: Removed Elm
And I think it is only a matter of time till someone writes a Swift-to-JS compiler (Apple might already have it on it's radar).
[1]: I know it is not a "build/dependency manager", but I don't know how to call better in for sake of this discussion.
npm install -g pulp purescript
should be enough now.