But intuitively it does make sense, because one of the primary effects of the drug is slowing down gastric emptying, so it causing heartburn isn't exactly surprising.
148 karma · joined March 5, 2022
But intuitively it does make sense, because one of the primary effects of the drug is slowing down gastric emptying, so it causing heartburn isn't exactly surprising.
I've lost significant amounts of weight (60+ pounds) three times in my adult life, through simple calorie restriction (intermittent fasting, including before I'd ever heard the term). Every time, I've gained the weight back. At the beginning of 2022, I was the heaviest I've ever been.
I've accomplished very hard things in my life, including those that take sustained effort. Sufficient willpower isn't a problem for me in general. I honestly only ever hear "it's easy, just eat less and move more" from people that have never actually been fat. "I did it and I lost 15 pounds, no big deal!" and the like. 15 pounds is easy for me to temporarily lose too. I've done it enough times I should know ;)
I've heard people say that the solution is to eat (healthy food) when you're hungry, and stop when you're full. The thing is, I'm never full. I can eat until I physically can't eat anymore (not something I do regularly, of course), and as soon as my stomach has emptied a bit, I feel fairly hungry again. "Eat until you feel full" is literally a human experience I had never really had.
On this drug, I finally know what people are talking about. I still like food, and I still get hungry. But it doesn't dominate my thoughts. I eat, and don't feel like eating again for hours. I eat something that I'd normally easily eat all of like a big burrito or whatever, and I feel quite full halfway through with no desire to finish. I'm steadily losing weight, with none of the usual preoccupation with hunger, ascetic adherence to a strict calorie plan, etc. But above all, I feel like I must be experiencing what most thin people experience all the time. I'll be perfectly happy to take the drug for the rest of my life, though I do hope affordability improves.
As for side effects: I've had some heartburn, but none of the other commonly reported side effects.
Honestly, it’s like a miracle. I’ve been fat since I was 6 years old. I’ve occasionally lost weight (though never made it to “normal”), but only through pretty intense, focused effort to restrict calories. I’ve always gained it back (and then some) after I can’t sustain that effort. (Call it lack of willpower or whatever, but this is how it works for the vast, vast majority of people.)
Anyway, on tirzepatide, it’s simply effortless. Food is still good, and I still like to eat, but I don’t think about it all day. I eat a reasonable amount, feel full, and don’t have the urge to eat again for hours and hours. That’s honestly a new experience for me. My entire life “eat when you’re actually hungry” would have meant eating all day every day, basically. I’ve been losing weight at a consistent 2.5 lbs / week on this drug. I fully intend to be on it for the rest of my life (or other drugs in the class as they come out).
As for side effects: I’ve had precisely none. No nausea, constipation, heartburn, etc. I understand those are common but I haven’t experienced them at all.
AppKit may go away eventually, but _today_ it's still required to write a good Mac app even if you can use SwiftUI for large portions.
My experience on this project has also taught me that AppKit can be made to play quite nicely with SwiftUI. The AppKit code is encapsulated well, and from the outside gets instantiated and included exactly as if it were a SwiftUI component.
Task.sleep(nanoseconds: 3e11)I'll also point out that the Mac had the same copy and paste keyboard shortcuts before Windows and Linux existed, so if any platform should be criticized for not matching, it'd be the one(s) that copied the shortcuts but added their own changes.
I don't use a Mac because everything about its UI is exactly the same as Windows and Linux, it's precisely the opposite. I use it because it's different (and IMO, better for me).
(And calling the window controls placement on macOS "wrong" is a bit rich. The platform that basically created the GUI can't be "wrong" about something so subjective as which side of the window those controls belong on.)
Anecdotally, my dad complains about paying an interest rate in the teens for the house I grew up in. My parents paid $69K ($188K in 2022 dollars) for the house, which was about a year old. Zillow estimates the same house at $457K today. Obviously not all of the price increase is due to lower interest rates, but the house _was_ much cheaper, so even with a high interest rate, the mortgage was pretty affordable.
However, seeing Ukrainians take up arms to fight an invasion has caused me to re-evaluate my position in general, and I actually think an armed population is likely better than the alternative. I'm sure Finland isn't unhappy that they're heavily armed right now.