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tylermcgrawon Can a wealthy family change the course of a deadly brain disease?

This is the model for rare diseases that wouldn’t be profitable for pharmaceutical companies. Spinal muscular atrophy (sma) is another example that comes to mind.

tylermcgrawon Ask HN: Who wants to be hired? (January 2026)

  Location: SF Bay Area
  Remote: Yes (open to in-office, hybrid, remote)
  Willing to relocate: No
  Technologies: Python, TypeScript/JavaScript, React, Express, FastAPI, Node.js, SQL, HTML, CSS, PostgreSQL, MongoDB, AWS, Docker
  Résumé/CV: https://tylermcgraw.github.io/resume
  Email: tyler.a.mcgraw@gmail.com

Hi there, I'm Tyler! I recently built Chunkwise, an open-source, self-managed platform that evaluates chunking strategies and deploys ETL pipelines for RAG systems. Check it out here: https://chunkwise.github.io/