Probably it is harder to scale startups in Europe vs the US. But is that something nations should optimize for?
And if so, what priority should be given to "ease of rapid growth for startups" vs many other issues that determine economic growth and a population's well being?
Also, how much of the problem is due to the issues you raise vs other factors such amount of money spent in R&D? The US has a huge amount of "defense spending" but in fact a lot of that is dedicated to funding research in Universities and direct job creation. Maybe Europe just needs more research Universities, more labs and more state investment into technology. The recent Moderna breakthrough was in part due to a $25 million DARPA investment into the RNA vaccine idea.
As for the issues you mention; solving bureaucratic issues would make things more efficient, and it is definitely desirable. However, I would argue that a heterogeneous market (in terms of language and culture) is more of an advantage than a liability.
Having many cultures and languages could be akin to having biodiversity. Different outlooks in life, different ways of expressing ideas, different ways of thinking can contribute to the development of culture and technology. Look at the Galapago effect that languages had in early computing. The Japanese were able to develop their own vision of "computing" and came up with their own innovations due in part that early western computers couldn't handle Japanese.
Languages and cultures can serve as natural protectionist barriers that allow for each region to develop their own home industries, allowing them to catch up to the world while retaining significant chunks of new wealth creation for their own. Yes, wealth creation is good, but its also important to look at how wealth is distributed. Very unequal societies can break down and lose their cohesion. Cohesion and trust are important features of rich countries. Perhaps many of the issues the US dealing with is because of the huge level of inequalities it has.
Finally, is translation and localization really that hard? Is it that expensive to hire some sales & marketing staff in new markets where you could be making tons of money? I bet translation costs and such are less than a percentage of what Google spent expanding its search engine.