sparsely

I had a quick look at what various special interest "non profits" had to say about this:

Alzheimer's Association -> very positive, basically an advert (https://www.alz.org/get-involved-now/new-day). " A new type of Alzheimer’s treatment, aducanumab addresses the disease in a way that has never been done before. This therapy slows progression of the disease, rather than only addressing symptoms."

Alzheimer's Foundation of America -> much more measured (https://alzfdn.org/alzheimers-foundation-of-america-statemen...) "We are hopeful that it will improve the quality of life for individuals living with Alzheimer’s disease and their caregivers. Patient access and affordability to all of those in need is of significant importance."

Alzheimer's Association transparency page claims that they received under $300k from Biogen in 2020 and that <2% of their revenue is from biotech - I feel like they are either selling themselves a bit too cheaply or being a bit dishonest. Their whole website feels weirdly corporate as well.

An absolutely shocking decision, which will have immense negative consequences for healthcare and healthcare costs far into the future. A license to turn false hope into profit margins and commissions for snake oil salesmen.

List price is $56,000 per year if you're curious.

First page of DDG found this: https://www.wired.com/2008/11/the-boy-who-cri/ (from 2008)

or this https://conversation.which.co.uk/motoring/breaking-speed-lim... it's from an insurer, but the % who admit to speeding is very high

or this from the UK gov https://assets.publishing.service.gov.uk/government/uploads/...

I think it's pretty widely acknowledged that speed limits are not effectively enforced on cars. And if they are, what is the cost to making the limitation (+10mph or whatever as required for safety) automatic?

Cities are requiring speed limiters on electric scooters and bikes, but I have never seen any serious suggestions from politicians that the same could and should be done on cars, despite the huge gap in danger.

I was about to make a comment that this felt like something from 10 years ago, but it turns out it actually was!

Lots of m43 cameras do some of the corrections in software, which does keep lens sizes and prices down.

We have speed limits on e-scooters and e-bikes, it's only path dependence that means we don't have them on cars, despite the obvious difference in risk.

Agreed. The nice thing about AWS is that they normally have at most a couple of different services that do what you're looking for, and you can be reasonably confident that they will work well and play nicely with all your other AWS hosted services.

No opinion on the thread, but his current startup involves streaming a chrome instance from the cloud, which feels very "Internet in 2021"

It's really great for exactly that use case, creating lots of internal dashboards from scratch. Part of how it makes it really easy is that you don't go through all the normal dev practices, and will normally connect directly to your datastores as well as any api endpoints your service provides. This creates a huge amount of deeply hidden coupling.

You'll also inevitably need to go beyond the functionality that retool offers, at which point their development experience really breaks down, and you'll have to either come up with some bespoke workflow to integrate complex custom components, or migrate away.

Despite all this I really like it as a tool, it just needs to be approached with care.

Nice article.

Ironically, using retool will inevitably generate massive tech debt in your organisation.

I agree that visual programming can be great - my argument would be that starting from a model that we know works and making incremental steps towards something more visual is more likely to succeed, than attempting to jump all the way to something fully visual based

It feels like this has been reposted regularly for years, but the demo videos and slightly threadbare use cases haven't changed at all. Re-imagining how we interact with computers sounds great, but it doesn't feel like this project is actually going to achieve it's goals beyond letting a small number of lucky users play around with stuff.

I'm not sure if darklang is going to succeed, but that seems like a far more fruitful direction to approach the problem from. It's a very hard problem, and they are attempting to make programming a little bit more visual while not removing any power from the user, instead of making it entirely visual and almost completely dis-empowering the user. Importantly, it's actually accessible to people all over the world, and they can use it to achieve real world goals.

Totally reasonable thing to want IMO.

Try searching for stuff to do with managing ETL/integrations. Some of these jobs will require loads of product involvement, others will be some not terribly interesting data munging. At your target salary level which you mentioned elsewhere (30k EUR), there should be plenty of positions where you'll exceed expectations with 2 hours of focused, intelligent work per day. Not sure how many will be remote though, sorry!

Why would they do this, and not have their own collectables database which they could more easily make money off?

The data in the article shows that life expectancy was significantly lower among European elites than it is now.

At 30, in the period they consider expected age of death was in the 60-70 range.

Now it's in the high 80s among ALL europeans in the region they consider, which seems like a pretty big difference.

"Seems like the amount of things we die from increased to match what we’re able to cure"

This is always going to be approximately true, unless we end up living forever somehow.

I feel like the author is really missing the point of this criticism. It's probably fine on an individual basis to work for (most) adtech companies like google. What sucks is the overall system which incentivizes the creation of arguably dangerous products and behaviours, even if by chance some of that money spills over into being spent on better causes.

Java is used all over the place for various backend applications, e.g. data processing, web backends. It's fast, well documented and has a great standard library and ecosystem. In many of these applications you control the deployment environment, so making sure that your container has the JVM isn't an issue.

I expected to agree with that article, but honestly the tradeoff seems reasonable. Given just the data presented there, is it actually worse if rent controlled apartments are hard to get if lots of people are also paying much less rent? I'd really want to see some data about lots of people wanting to move to or within Berlin who are not able to due to lack of supply. That data may well exist but isn't presented here.

Often getting an account in another country is a big hurdle - TW makes this incredibly easy.

e.g. I'm opening an account in France at the moment (as a French resident!) and it is taking literal weeks and lots of scanning documents, posting paperwork, phone calls etc. TW opened a Euro account for me in a few clicks.

Really interesting article. The intro and conclusion suggest that there is some sort of debate going on about usage of "Anglo-Saxon", but I cannot work out what it actually is and what side the author is on.

It's true, energy markets are entirely unresponsive to supply and demand and contain no feedback loops.

That is at least 1 order of magnitude cheaper than I would have guessed. Mind boggling that it's cheaper to do that then buy like the 4th best meal delivery app in Canada or whatever.

This is a very weird rant, is "Wall Street" actually terrified or are some talking heads on CNBC just making up some drama?

There are 110 long shares worth of economic interest in the company - the original owner will still report the shares they have lent out when looking at their current position.

Pretty incredible that the simulations take "many months" to run on what I presume would be a supercomputer of some sort. What sort of resolution are they modelling these events at?

vscode does this when you open a C# file already, makes it very easy to get started.

I think this was a great idea btw, sorry that it didn't work out. Before covid I always used to try and find audio walking tours for cities, and alternative ones to the normally rather dry official ones for museums, but there really isn't much out there.

I don't quite get the actual mechanism by which this incentivizes energy efficiency investments, or why blockchain is required vs normal debt, but the "blockchain, but for climate solutions" idea appears in "The Ministry for the Future", where it also looks like a weird idea.