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skue

1,445 karma · joined February 28, 2011

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skue··on Theranos Trouble: A First Person Account
> There are too many variables at play, and numbers can change between morning and afternoon even on the same day depending on the test.

Respectfully, you are making a broad, inaccurate statement and assumedly without a medical background.

While it's true that some numbers can change even on the same day (Gassée specifically mentioned glucose as an example of a lab value that can fluctuate quite a bit), the concentration of red blood cells and platelets is not affected by what you had for lunch and definitely should not vary this much. Keep in mind that the difference Gassée saw was was almost enough to trigger unnecessary therapeutic phlebotomy.

skue··on Elon Musk says Apple is the 'graveyard' for fired Tesla staff
By whom? The Post link you provided didn't mention Musk, and it's an odd, poorly-organized article that conflates drivenness and social awkwardness with Aspergers, when they're not necessarily the same. People with Aspergers are more likely to be socially awkward, but not everyone who is socially awkward has Aspergers. This Post article even includes a story from the Isaacson bio about a young Steve Jobs (who didn't have Aspergers) disrupting a meeting for Seva, while omitting Jobs' emotional reaction and subsequent apology as soon as he left that meeting.
skue··on Give Google Contributor a try: Pay to remove ads
This still gives Google the ability to track the web pages we visit, and many of us block ads because of tracking, not because they're ugly.

That said, I do think that solutions like Google Contributor are the way forward if it can become an open standard that supports anonymization. I'm willing to trust my browser and a local, open-source wallet to watch the sites that I visit and authorize micro-payments via an anonymous currency. Those payments could be delivered to websites via middlemen that include ad vendors like Google or other processors.

It would require careful design and numerous security considerations, but it seems possible to use this model to support publishers while maintaining privacy.

skue··on When Phone Encryption Blocks Justice
For those in the US, here is contact information for the Manhattan DA's office. Although Cyrus R. Vance Jr. was speaking as an elected politician, the main operator and press office were not sure where to route incoming calls from voters, so here are a few options.

  Main:  (212) 335-9000
  Press: (212) 335-9400
  Cyber: (212) 335-9600 (Hotline)
If you prefer email, I was told to use press@dany.nyc.gov

Please think about what you will say beforehand, be very polite, but be heard. And given that Vance wrote alongside DA's from France, UK, and Spain, there is no reason to not call if you live outside of Manhattan.

We should probably share similar information for the offices in London, Paris, and Madrid.

skue··on Humans should think of sizeof() as a function, says Linus Torvalds
If you have an argument to make, then make it.

The previous poster didn't say he was unwilling to learn JS semicolon rules, he was saying he couldn't trust everyone he ever works with to learn them. Replying with an accusation of FUD and a link to someone ranting that it's unprofessional for JS devs to not know these rules is unnecessarily inflammatory while missing his point.

skue··on Let’s all laugh at my horrible 2006 post: “YouTube is not a real business”
> The fact that they were forced to sell a business that is now worth $100-150b for $1.6b is a good indication for how close to the brink of destruction they were.

As a founder, I dream of having a company that close to the brink of destruction.

skue··on The Common Cure for Heroin Addiction Is Also a Magnet for Police Harassment
Had the same reaction and even pulled up the BuzzFeed home page, wondering if they had refactored their style. Nope! The main page is still full of crappy linkbait lists... but here's hoping they do more articles like this.
skue··on The Common Cure for Heroin Addiction Is Also a Magnet for Police Harassment
My immediate reaction upon reading this headline and story was "Wait, this is in BuzzFeed?"

Probably the first time I've noticed a BuzzFeed article on HN, definitely the first time I've upvoted one.

skue··on The Common Cure for Heroin Addiction Is Also a Magnet for Police Harassment
The headline should have called it a "treatment" rather than a "cure," but methadone is a legit treatment. Agreed that getting folks on suboxone would be even better, but from a public health perspective it's still preferable to switch heroin addicts to methadone because it's safer and - by being dispensed freely - can reduce drug-related crime.
skue··on If you are storing important info in Evernote, think twice
> I thought it was already well known that Evernote software cannot be trusted.... I'm baffled that users continue to trust it.

It's unfair and condescending to blame the user when companies like Evernote actively mislead them. The service called Ever-note, with an elephant as their logo/icon. Their website even features this slogan: "Your life's work. For everything you’ll do, Evernote is the workspace to get it done."

Most HNers realize that cloud syncing and backups aren't the same thing, that cloud services do fail, and when they do customer service is likely to be woefully unhelpful. And that the marketing departments at companies like Evernote overpromise because it serves their growth strategy and they never face repercussions. But that doesn't mean that any of this is okay.

This is on Evernote not its users, and we only help Evernote when we downplay this as old news or presume average users should adopt some of the far too sophisticated alternatives mentioned in this thread (like org-mode).

skue··on First U.S. Bitcoin Exchange Set to Open
Is there any significant difference between this exchange and the upcoming Winklevoss exchange?[1]

Both claim to be "regulated," but it doesn't look like the Winklevoss version will offer SIPC protections either.[2]

[1] http://dealbook.nytimes.com/2015/01/22/winklevoss-twins-aim-...

[2] http://www.sec.gov/Archives/edgar/data/1579346/0001193125132...

skue··on Zipcar vs. Car2Go
I wonder if there is a significant difference in the drivers who choose Car2Go. The first time I saw a Car2Go vehicle was in Portland, when I had to react because the driver did something foolish. I remember doing a double take to see if someone was training a new driver, and being surprised to see the carshare logo and a middle-aged driver behind the wheel. I figured it was a one-off... until a week later when I had a similar experience with a different Car2Go vehicle... and then a couple weeks later with a third.

I can't recall ever having an issue with other car share drivers, but I pay extra attention whenever I spot a Car2Go and make sure to give them a wide berth.

skue··on Apple kill third party SSD support in Yosemite
Please don't upvote this article. It appears to be someone jumping to a wild conclusion.

I, like the other commenters, installed Yosemite on a third party SSD and it works great. If this were a common problem it would have affected many people and we would have heard about it months ago, back when Yosemite was in beta.

Maybe there is an issue affecting some users, but if so then it is far more likely a bug than some underhanded scheme. And given this blogger's problem solving abilities ("There's a problem... Apple must be trying to harm me!"), my bet is that it's simply a case of user error.

skue··on Reflected File Download: A New Web Attack Vector
> are there examples where attackers gain a big advantage by having a downloaded file come from a trusted URL?

Yeah. I hope Adobe is all over this.

It's not hard for me to imagine a shady website that offers streaming videos prompting users that they need to update Flash, then redirecting the user to an adobe.com URL that downloads an installer. I bet even some savvy HNers could fall for that.

Or how about a similar attack on enterprise users by prompting them to update Adobe Reader.

skue··on Kickstarter Freezes Anonabox Privacy Router Project for Misleading Funders
Hooray. This project was misleading and naive in many ways, and it definitely seemed to violate Kickstarter's rules against resale. But that's not why I'm happy this project got killed.

The much bigger problem was the open SSL account and sheer misguidedness of running all network traffic through Tor. This project risked causing real harm to people thinking that this would safeguard their privacy.

skue··on A Device Could Detect Dozens of Cancers with a Single Blood Test
No, no, no. This is a perfect example of why everyone should be required to learn statistics.

We don't need a device to do multiple simultaneous screenings. If this were important, we'd already be doing multiple manual screenings and there would already be a demand for simplifying it. But there's a very good reason we do not do mass screening for cancers and other serious diseases with low incidence, no risk of transmission, and invasive treatment regimens.

Medical tests are not crystal balls. Any test you perform has a risk of false positives and a risk of false negatives, and even if you have a test with good specificity and sensitivity, applying any test to any large population with a low incidence of disease guarantees that most of the positive findings will be wrong.[1]

Telling hundreds of thousands of healthy people that they have cancer and sending them through intensive workup and/or treatment when they actually do not is emotionally and financially harmful to them and the broader community.

This is why we do not do population-wide CT screening for lung cancer, why we no longer stress that young women without other risk factors have mammograms (but can choose to if they are risk averse and are okay with potentially receiving unnecessary treatment), why we are moving away from aggressive PSA screening, etc.

What's the alternative? Targeted screening. If you reduce the size of people you screen to those most likely to be affected, then you dramatically improve your results. So people with symptoms (obviously), people with certain exposures (asbestos), genetic predispositions to certain types of cancers (BRCA), etc. In other words, the thing that works best is what we already do.

[1]: http://en.wikipedia.org/wiki/Sensitivity_and_specificity#Wor...

skue··on Artificial sweeteners linked to glucose intolerance
For those not aware, other studies have shown that consuming diet soda may actually increase the chance of obesity. So that is not necessarily news. If you are curious, here is a pretty good study (full text):

http://onlinelibrary.wiley.com/doi/10.1038/oby.2008.284/full

More recently, studies have tried to determine whether there is a satiety or protein mechanism that can explain this, whereas this new study demonstrates that gut flora may play a role.

This needs to be confirmed, and there may still be other mechanisms at play as well, but it is interesting.

(Disclaimer: I do have a healthcare background, but am not a researcher in this field. Would be happy to hear more from anyone who is.)

skue··on Feds Threatened to Fine Yahoo $250K Daily for Not Complying with NSA's PRISM
Right, but what would that look like? Would the FISA court jail a citizen without a trial, and can you imagine a FISA judge wanting to make that call, knowing that their decision will soon become public? Because once someone is prosecuted the U.S. govt would really have difficulty enforcing silence. It's one thing to force a company to be silent about surveillance, it's quite another to force individuals to be silent about being jailed. I'd like to think we haven't gone so far off the tracks that the first amendment wouldn't ultimately triumph in that case.
skue··on PullClean: Door handles as sanitizers
UV sterilization works by disrupting the DNA of pathogens -- which is exactly the same mechanism that causes skin cancer. So I don't see this product arriving anytime soon.
skue··on PullClean: Door handles as sanitizers
Can you provide references?

That may be true of your basic drugstore Purell, which just contains ethyl alcohol. But the literature does indicate that hospital-grade hand sanitizers (a blend of alcohols, and/or a non-alcohol equivalent) are far superior and immediately effective against most organisms.

See for example, http://cmr.asm.org/content/17/4/863.short

skue··on Recommended Security Reading
I agree that _Design Patterns_ has little to do with security, but I think you are being a bit hard on it from a programming perspective.

Certainly the book is tremendously useful for ObjC programmers because Apple incorporated most of these patterns into Cocoa and Cocoa Touch. And as someone who has done code review with junior Android developers, I wish that more devs read it. When a security researcher refers to a MITM attack or SQL injection, this higher level concepts mean something and it enables clearer conversation. That's what design patterns provide to software developers.

skue··on ITerm2 2.0
I agree with your sentiment and it is depressing to see you downvoted. On HN I would have hoped your comment would stimulate those familiar with the code base to offer hints of where to start hacking, rather than rapid down arrow clicks.
skue··on Women's underwear gets an upgrade
Dear Kate is another company has been working in this space for years: http://www.dearkates.com/pages/technology

Their CEO Julie is great - studied chemical engineering at Brown, was very active in the local RI startup scene, raised a series A, and the company is now based in NYC.

skue··on The Design Of SQLite4
Hopefully there aren't many people designing data models with NULL primary keys.

However, if SQLite never enforced non-NULL behavior then it's certainly possible that along the way some applications could have written an errant record to a database with a NULL primary key (instead of treating it as an error case). And if a "fixed" version of SQLite3 ever shipped, then these previously-valid data files would suddenly become invalid.

Imagine being an app developer and having random customers whose data files suddenly break because the OS happened to upgrade the SQLite3 library to a version that included this fix. I completely understand why the the SQLite maintainers may have decided it wasn't worth the hassle to fix things prior to SQLite4.

skue··on The Internet Is Burning
> I’m pleased that I was a Heartbleed hipster, dissing OpenSSL before it was cool (i.e. ten days before Heartbleed emerged into the light) but I don’t pretend to be a security expert.

When did it become appropriate to diss open source software without the expertise to create something better, and why does he think this is brag-worthy?

skue··on 37 percent of adults cannot swim the length of a 25-yard pool
So maybe it's a good thing Americans are becoming more buoyant?

I'm joking of course, although the number of unintentional drownings in the US has been dropping steadily since the 80s, and researchers have not been able to fully explain the cause...[1]

[1]: http://jama.jamanetwork.com/article.aspx?articleid=190416

skue··on Yahoo ends support of “Do Not Track”
I used to feel that blocking online ads was freeloading, but I am increasingly convinced that the online ads are a failed experiment and it's our duty to kill them -- especially when the industry can't even follow through on watered-down self-regulation like DNT.

The crazy thing is that major websites like Yahoo don't even know what ads they are serving. And increasingly online ads are an attack vector for viruses and malware. In January Yahoo was serving malware via their online ads.[1] And in February Google did the same.[2]

And of course there are the major privacy issues with companies tracking us online. I understand that online publishing is important and we clearly need a strong press, but publishing really needs to find a new business model. Online ads are not the solution.

[1]: http://www.cnn.com/2014/01/05/tech/yahoo-malware-attack/inde....

[2]: http://labs.bromium.com/2014/02/21/the-wild-wild-web-youtube....

skue··on Apple, Facebook, others defy authorities, notify users of secret data demands
No, this is different. In the past, tech companies might comply with requests from prosecutors to not inform customers that their data has been requested. This story claims that tech companies now require a gag order from a judge (FISC or otherwise).

I have a lot of issues with FISA, but it sounds as though FISA requests are a far rarer than prosecutors requesting records. To restore balance we really do need to get back to requiring judges to weigh each request for data individually.

skue··on Show HN: Ditto – Markdown documentation system
I assume you searched and discovered that ditto is also a BSD command for copying files, which is included on all Macs?[1]

This conflict may not be as confusing as the original name. I gather from the docs that you never invoke your version of ditto from the command line?

[1]: https://developer.apple.com/library/mac/documentation/Darwin...

skue··on Server-Sent Events: The simplest realtime browser spec
Yes, the umbrella term for this HTTP server push is Comet[1], and it's been around in various forms for years. But standardizing this in the form of server-sent events is a very Good Thing, especially with support baked into modern browsers.

Also, unlike WebSockets it's also easy to add SSE support for mobile clients. I've implemented a SSE client class in just over 100 lines of Java, and it's similarly easy to do this with NSURLConnection/NSURLSession on iOS. The W3 standard provides an implementation section that reads like pseudocode.[2]

[1]: https://en.wikipedia.org/wiki/Comet_%28programming%29

[2]: http://dev.w3.org/html5/eventsource/#event-stream-interpreta...

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