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randogp

44 karma · joined June 5, 2015

meet.hn/city/46.5218269,6.6327025/Lausanne
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randogp··on Mars Bar from 1991 found – and it's 20g bigger than today's
The Acquired podcast covers the full family history https://podcasts.apple.com/us/podcast/mars-inc-the-chocolate...
randogp··on How to sequence your own DNA at home
How will you reach out to enough people so they are aware and can order the service? I'm thinking about the minimum viable business opportunity here.
randogp··on The Alchemist of Flesh: The Man Who Turned Humans into Stone(2025)
At the time, Italy counted other "single contributor" petrification fellows. See https://www.museogorini.com/pietrificazione_eng.php

Curious if that was also present in other countries.

randogp··on Avian Visitors
Upvoted for the Theobroma cacao reference. Made me curious about what you are up to.
randogp··on Craig Venter has died
At the time they announced the full genome sequence I was an intern in molecular biology. We had a thermocycler in the lab and I had to book my slot on a paper agenda. I remember this portrait of him in front of multiple racks each plenty of thermocyclers. He taught me something about scale and he proved that sometimes it's worth looking at what you have and ask what if I could 200x this. In software this might seem obvious with GPU arrays etc.. but when you are trained in a wet lab and the instrument paper agenda, I wonder if we could have more breakthroughs in life sciences if we could use some bruteforce now and then. RIP
randogp··on Show HN: Craftplan – I built my wife a production management tool for her bakery
Awesome, does it support Semiproducts? For example I'm making my own jam (sugar + fruit) and then I use this again as a material in different finished products, say cakes and croissants.
randogp··on Two recently found works of J.S. Bach presented in Leipzig [video]
Apparently the works were known since long time, not 'recently found' as the title suggests. The novelty is the authorship attribution to JSB.
randogp··on Sequencing wastewater may be key to getting a grip on the H5N1 bird flu outbreak
The EU publishes monthly bulletins around DNA surveillance programs. "The bulletin summarise the reported results and findings from European national wastewater surveillance programmes. It also informs about the local surveillance projects and non-EU countries participating as observers" https://wastewater-observatory.jrc.ec.europa.eu/#/bulletin
randogp··on Lactic Acid Bacteria as Markers for the Authentication of Swiss Cheeses
The article is from 2016. Update 2018: development of a rapid test for cheese authenticity https://www.foodauthenticity.global/new-services/new-test-fo...
randogp··on List of Common Misconceptions
This, with some illustrations, could be a fantastic book for kids and adults.
randogp··on "To our surprise"
and patents as well https://patents.google.com/?q=%22to+our+surprise%22
randogp··on Iridescent Tempered Chocolate
A Swiss startup worked in this direction to offer brand protection and consumer engagement http://www.morphotonix.com/chocolate/
randogp··on The Beginning of the Monte Carlo Method (1987)
I'd love to have a web-app for that
randogp··on Italian doctors successfully transplant a kidney in the place of the spleen
Intentional.

Both kidney and spleen filter blood, although spleen is not essential and can be removed (splenectomy). Sacrificing the spleen, the surgeon used the spleen vessels to connect the kidney to the blood circulation. Reading the Italian news, the vessels of the other kidneys were in bad shape.

randogp··on Misperceiving Bullshit as Profound
Apparently, in the article's comment section the word "bullshit" triggers a profanity filter.

http://journals.plos.org/plosone/article/comment?id=info%3Ad...

randogp··on Scientists Unveil the 'Most Clever' CRISPR Gadget So Far
I love when someone digests for me the article and gives just the facts.
randogp··on BrewDog’s open-source revolution is at the vanguard of postcapitalism
Would be great to have machine-readable data. Any hint? (sorry if it is obvious my background is in wet lab biology)
randogp··on Death by Coconut: A Story of Food Obsession Gone Too Far
This Death by Coconut reminds me some mice from my colleague Jun.

These mice had a mutation in one gene but they were doing fine.

One Friday Jun gave them a chow diet from another supplier. The following Monday all mutant mice were died, control mice were OK.

TLDR, the new diet contained coconut oil instead of lard. After more study, this serendipitous observation led to discover a gene important for the break down of vegetal fat.

The study: http://dx.doi.org/10.1016/j.celrep.2013.08.032

randogp··on How the Body’s Trillions of Clocks Keep Time
Working in the that lab right now. We can now follow the oscillations of these proteins inside the mouse without kills. Wawesome.
randogp··on Garage Biology in Silicon Valley (2010)
To handle liquids on that volume range, biologists use micropipettes. These can be operated by a robot: https://www.youtube.com/watch?v=3ouPBX65kXU
randogp··on Ask HN: Things to Do in Amsterdam?
If you are into (hacking | making | DIYbio) consider a visit to Waag http://waag.org/en