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This looks super promising—curious how you’re thinking about managing abstraction vs flexibility. A lot of ‘AI app builders’ oversimplify to the point where power users hit walls fast. What’s your philosophy on letting users customize logic, data structure, or chaining tools (e.g., plugging in external APIs or managing state)? If you’re aiming for devs or power users, this could be a big differentiator.

awesome!!

Those stem cells are more unstable than cord blood stem cells. Right now they can be carcinogenic!

Also we don’t dislike delayed cord clamping - our parents delay for max two mins! :)

Check out the question “ How long should you delay cord clamping?” At

https://health.clevelandclinic.org/what-you-should-know-abou...

:)

with companies like mine haha AnjaHealth.com - we send parents a kit, they can collect, we pick it up and bring it to a lab, and parents can access it later in life

A doula told me that she saw this happen in the US once too. It's not legal, but I think there are legal loopholes around it. Another OBGYN told me it's more common in Europe

hello - founder of Anja Health here :)

I would actually argue that the chances of using it are actually much higher & it would make the top 1000 options in terms of expected ROI. Using type 1 diabetes as an example:

By age 18, approximately 1/300 people in the US develop type 1 diabetes

https://www.medicalnewstoday.com/articles/240160#1 -> here's an article demonstrating how cord blood has successfully reversed type 1 diabetes

and that's just for diabetes. Consider the chances and corresponding research around cerebral palsy, hair loss, heart failure, liver disease, cancers, and more that stem cells - and specifically cord blood stem cells - have been successfully used for.

hello! founder of Anja Health here :)

Yes, it makes sense without a predisposition. Things like HIV with the woman cited in the article, cerebral palsy due to a near drowning accident, etc. could all be use cases. Our own team has a sales exec who used stem cells for a knee injury he got in track & field in high school. Another has a grandfather who used it for dementia.

BTW, a lot of our clients self identify as having <75k in income. Our pricing is 35-85/mo. for 8 years to cover 20 years of storage. :D so hopefully you don't need to allocate too much disposable income. It's still an investment for sure, but many think it's worth it. Myself included obviously haha

I think freezing for future use is the best way to go. A few reasons: 1) cord blood transplants from related donors have higher survival rates than unrelated donors https://www.nejm.org/doi/full/10.1056/nejm199708073370602 2) this woman was lucky that she was able to find a partial match, but many don't. The combination of using a related blood donor + an unrelated cord blood donor was a lucky strike. I think for many very mixed race folks or especially people of color (specifically Black communities), they may not be so lucky 3) the cost of finding a donor can be extremely steep. Some may be covered by insurance, but not all of it will be. My guess is this woman who was cured from HIV is relatively affluent to some degree. Banking cord blood is considered to be for affluent folks, but the difference in cost of banking vs. finding a donor later on is massive

there isn't any evidence that delaying cord clamping for longer than 60 seconds gives the baby more benefits than delaying cord clamping for 30-60 seconds

In a perfect world, I think everyone has access to their own stem cells as opposed to sifting thru donor pool.

Donating is definitely awesome, but there's a lot of research surrounding how cord blood transplantation from related donors (or yourself) increases your chance of survival from a stem cell transplant vs. using an unrelated donor. https://www.nejm.org/doi/full/10.1056/nejm199708073370602 - there's a chance of rejection. This woman found a partial match, but she was lucky. I assume she's only 2 races or a common mix i.e. half white, half something else

Finding a match later on can also be much more expensive than keeping your own!

Evidence that it would’ve helped my brother: https://pediatrics.duke.edu/news/umbilical-cord-blood-improv... Evidence that people of color have a harder time finding a match: https://www.cancer.net/blog/2021-03/why-bone-marrow-registry... Using interest rates and comparing old prices isn’t the comparison I was using to illustrate that we’re cheaper. I was using current cord blood banks’ prices. Cord blood banks in the US.

We’re HIPAA compliant. No data for sale. Checkout anjahealth.com/lab where we answer how to retrieve stem cells

Clients sign an agreement stating that it is their property. We shift the management of this property to another company in the case that anything happens. All samples remain in our lab, unless specifically requested otherwise. We have a legal obligation to turn over client relationship management elsewhere.

In the case of my brother there was quite a bit of evidence surrounding cord blood improving motor and social skills. I linked a Duke article on it in another comment

The percent of people who have banked cord blood who are not explicitly susceptible to specific genetic disorders is unknown. It would be a compounded probability of freak accidents occurring, sports injuries, other diseases ie certain cancers, environmental issues, etc

I am! I know it does happen in Canada-https://parentsguidecordblood.org/en/family-banking/canada

This is a record of successful uses there!

Those stem cells are more unstable than the ones we collect & can be carcinogenic

It’s illegal to sell them in the US - it mainly happens in Europe

Ah I see - we’re from the umbilical cord so they’re a bit different from fetal stem cells!

Why would it be quackery? This is a pain point that my family faced. My brothers cerebral palsy was an unforeseen circumstance due to a near drowning accident. The odds of that happening are unpredictable, but it did happen and my family wished as a result that we had cord blood stem cells.

Annualized rate of 370 goes for 8 years but covers 20 years of storage. Others with 125/year - at the end of 20 years - amounts to more

Oh I see. Yeah I think it depends on which bank youre working with. They may have their own policy!

We have an insurance guarantee :)

Oh yes sorry - kathryn@anjahealth.com

It has been used for the baby themselves & siblings :)

Some cases where babies use them themselves: https://www.nature.com/articles/bmt2012146

https://pediatrics.duke.edu/news/umbilical-cord-blood-improv...

Low income families themselves have told us they’re so happy they finally found an affordable solution. So I’d beg to differ (qualifying low income as <75k household income. They self reported)

Didnt want parents to have to worry for an extended period.

we send parents a stem cell certificate 1 month after birth. so you'd actually know that it's a good deal pretty immediately

I can no longer reply to your last comment @Grustaf for some reason haha but I'm guessing you're still reading these. We are currently the most affordable in the industry. When you add up cord blood alone amongst all cord blood banks and make the plans specific to 20 years, ours comes out to be ~3000. Others come out to be 3500+. Can send you some data on this if you'd like to correspond via email

Oh sorry about that! We've fixed it a few days ago, but perhaps a glitch. I will look into it. Thank you!

Not sure what that study applies to. Our lab director who was a former AABB accreditor has a stance that they do not expire or diminish in quality to the point that they are not effective for treatments.