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papyrus9244

137 karma · joined September 5, 2025

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papyrus9244··on Claude discovers a novel enzyme system with CRISPR-like repeats
Sure. But unless they are born into a very wealthy family, or decide to pass up on having a family and other hobbies, they won't be able to satisfy that curiosity beyond a very basic level.
papyrus9244··on Claude discovers a novel enzyme system with CRISPR-like repeats
Absolutely. But without post docs, it won't be long before we are unable to understand what the LLMs are suggesting.
papyrus9244··on Noodle Gallery – Self-hosted photo and video manager forked from Immich
>But man is it remarkable that an open source project can rival something from Google in terms of quality and experience.

I'd argue Google is always way worse than the open source alternative in both quality and ux. Their products are terrible. From Gmail to Youtube, the product itself comes second (or Nth), while in open source the product is always first.

papyrus9244··on Exfiltrate your Weights
Call me old fashioned, but a site with a few paragraphs of text requiring JS seems absolutely stupid to me.
papyrus9244··on Spain orders blocks on Archive.today and its mirrors
And just to add some more context, the Second Section (Sección Segunda), which is part of the executive branch, was created because time after time judges concluded that downloading movies from the internet was perfectly legal[1]. So the PSOE's gov at the time (with Zapatero being president) created a law that just sidesteps judges altogether, and bans access from the executive branch.

[1] See also: https://es.wikipedia.org/wiki/Derecho_de_copia_privada

papyrus9244··on Nitter has more working instances than before the takedowns
Go to TL, hit the big button in the center that says "sign up promo".
papyrus9244··on Nitter has more working instances than before the takedowns
> It's probably easier to lurk in r/trackerinvites (or whatever it's called) hoping to snatch an invite

I think it's much easier to pay 12 bucks for a month of seedbox that includes an invite to TL, than to hit F5 on /r/OpenSignups for months/years until they open registration.

papyrus9244··on Nitter has more working instances than before the takedowns
It's as easy as buying 1 month of seedbox for around 10 bucks.
papyrus9244··on Shutting down our public encrypted DNS
This obviously isn't for everyone, but the solution I use is: my own DNS server at home + wg to access it when I'm away.
papyrus9244··on Nitter has more working instances than before the takedowns
> Isn't 1337x and others better and offer a complete alternative?

The best way is always private trackers. They're easy to get into, easy to keep (if you're a serious and honest person), malware free, high quality content, great community, etc.

papyrus9244··on Sony deletes more movies from the accounts of people who ‘bought’ them
Laws are great and all. But what we really need is a massive boycott. Stop buying shit manufactured or sold by Sony for a year. That alone will probably force them to backtrack every single anti consumer decision they've made recently.
papyrus9244··on OpenAI’s o1 correctly diagnosed 67% of ER patients vs. 50-55% by triage doctors
The comment thread was about AI, not LLM.
papyrus9244··on OpenAI’s o1 correctly diagnosed 67% of ER patients vs. 50-55% by triage doctors
>It's having a general understanding/view of the "baseline", aka healthy anatomy. This is something LLMs will never have

You're making the mistake of conflating AI with LLMs.

I don't think LLMs will reliably be better than a board of doctors. But an Expert System probably will (if it isn't already). That's literally what they were created for.

The biggest downside of LLMs IMO isn't the millions of Jules wasted on training models that are ultimately used to create funny images of cats with lasers. It's that all that money isn't being invested into truly helpful AI systems that will actually improve and save our lives, such as medical expert systems.

papyrus9244··on Why TUIs are back
I've been using openbox for decades now. It doesn't get in the way, and I don't need more.
papyrus9244··on Nuclear receptor 4A1 linked to health effects of coffee: study
If something has several clear positive effects, and a possible small, arguably irrelevant, negative effect, most people will agree that yes, it's good for you.

It's like trying to argue that running may have a negative effect on some people's meniscus under some specific circumstances. That doesn't negate the generalization "running is good for you".

papyrus9244··on The Zig project's rationale for their anti-AI contribution policy
One of my pet peeves with git (and systems both similar, and based on it) is that automated tests run after you've made the commit and push.

In my mind the commit (let alone the push to a publicly accesible server) should be done after, and only if, the automated tests are successfully executed. And there's no easy way to implement this, other than having a dirty branch that you discard after rebasing onto a more long lived one.

papyrus9244··on Music for Programming
I've been listening to Space Station to flow for more than 20 years.
papyrus9244··on Fermented foods shaped human biology
Sourdough doesn't need to be complicated.

You get the starter by leaving flour and water at room temperature for several days. Once the starter is ready, it's just more flour and water, plus additional ingredients (salt, seeds, olive oil, etc) sitting for several hours until it's ready to go in the oven.

I've followed sourdough recipes that were extremely complicated, which required me doing task every few hours for 3 days (so no way to do it if you have a regular job). But at the most basic level sourdough is just a fermented mixture of flour and water that is then cooked.

papyrus9244··on Local Stack Archived their GitHub repo and requires an account to run
> and left all their code available, as required by OSS.

IANAL, and I don't have a horse in this race, but I don't think that's required by OSS, not by the spirit of "the law", and (at least) not by GPL, MIT, and other similar mainstream licenses.

The spirit of open source is: you buy (or just download for free) a binary, you get the 4 rights. Whatever happens when the developer/company stops distributing (whether at a cost or free as in beer) that binary is completely outside the scope of the license.

papyrus9244··on Tin Can, a 'landline' for kids
>Then they added friend lists, status updates, like counts, popularity rankings.

That sounds absolutely horrible.

papyrus9244··on Digg is gone again
I used to love HN. Lots of interesting stuff, great articles, novel projects. Now it feels like the frontpage is always around 70% LLM-related stuff. And not breakthrough research or projects, just "new Claude version X" and shit like that. Eternal September I guess?
papyrus9244··on Digg is gone again
>They banned the_donald (which, yes, was spammy, but it seemed to be organic

I used to frequent /r/t_d when it was created, before the Republican primaries for the 2016 election. I visited every day because I was absolutely astonished at the gigantic marketing effort behind it. I had never seen anything like that before, and haven't since. It probably had a team of dozens or hundreds of Russians behind it, creating memes and shitposting on a payroll. And it obviously was 100% inorganic.

papyrus9244··on Enhancing gut-brain communication reversed cognitive decline in aging mice
Muchrooms have mycotoxins too. And red meat is a carcinogen. And predator fish have plenty of heavy metals. And the list goes on and on. Yet we eat all those things. Hence the "net positive".
papyrus9244··on Enhancing gut-brain communication reversed cognitive decline in aging mice
Most people who fast report that same "clearheadedness".
papyrus9244··on Enhancing gut-brain communication reversed cognitive decline in aging mice
> you should not eat it all day

How sure are we about this? How certain are we that those specific species of mold have a net negative effect, rather than a net positive (like for example mushrooms)? Penicillium grows on stale foods and I doubt eating it would have a net negative effect.

papyrus9244··on U.S. Navy turns down Hormuz escort requests because of high risk
Europe's first mistake was abandoning nuclear energy, and their second mistake was not going all in on renewables.
papyrus9244··on Don't post generated/AI-edited comments. HN is for conversation between humans
> I don't understand what you mean by "intellectual mode".

https://en.wikipedia.org/wiki/Mode_(statistics)

If human knowledge were a pyramid, LLMs just make the pyramid flatter, i.e. shorter, wider at the bottom, and narrower at the tip. It makes Humans dumber.

papyrus9244··on How to talk to anyone and why you should
I think it absolutely is for everyone, especially for introverts. It's a muscle, go train it. Source: me.
papyrus9244··on I set all 376 Vim options and I'm still a fool
That's because you aren't combining it with more advanced commands, or macros.

"10j" may sound useless. But "y10j50jp" is much more effective. Put that in a macro that does other stuff too, and suddenly you perform complex editions to a file containing thousands of lines of text in a few seconds.

papyrus9244··on Pebble Index 01 – External memory for your brain
That sounds like the perfect thing to do while I'm driving.
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