Recreational use of MDMA has given me panic attacks, increased anxiety, emotional dependence and depression. There is a lot of anecdotal evidence online that tells the same story, which is something you rarely hear anyone talk about. It seems like different people respond differently to MDMA. Perhaps it's dependent on your personality or brain chemistry. For people like me the effect on the serotonin system in the brain can be very dangerous and sometimes cause permanent damage.
I used to be very liberal towards drug use in general until I experienced the down sides first hand.