At the same time, I can see this as being a useful tool for saving lives.
It's funny I'm seeing this actually. I'm actually on kratom right now, I bought some earlier today. I didn't really want to, I don't want to be on kratom because it's opiod like and expensive and can cause dependence. But I was getting so down that I was seriously worried I was going to kill myself, so I took it as an antidepressant.
I suffer from treatment resistant depression. Part of it is genetic (depression runs in my family) and I'm sure a lot of it is environmental (being minor attracted in our current society fills me with feelings of self-loathing and worthlessness) After trying a bunch of different SSRIs and SNRIs, I finally found a treatment that worked: Ketamine. I went to a clinic and got infusions, then was given take-home troches. It was amazing. Every time I started to get depressed (every few weeks), I would take a troche and abort that cycle of depression. My friends couldn't believe it. That combined with self-practiced CBT has really helped.
However I recently moved and no clinic in my area will offer prescription ketamine due to concerns about abuse. Okay, whatever...I could go in and get infusions. But every infusion costs ~$500 per session. Ketamine is prescribed off-label for depression, so insurance does not cover it. That's because nobody has funded the clinical trials necessary for the FDA to approve ketamine for depression. Despite the fact that everybody knows it's one of the best treatments for depression, it's generic, so drug companies have no profit incentive. There's esketmaine, but I've heard mixed reviews and popular opinion seems to point that it isn't nearly as effective.
I wonder how many millions and millions of people, including people who are using opiods as an antidepressant, would benefit if some group (maybe the government) would just pay to get ketamine on-label for depression, and thus covered by insurance. I feel like that would do more to lower opioid abuse than a million high school DARE presentations...