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kikokikokiko

280 karma · joined August 6, 2018

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kikokikokiko··on Claude discovers a novel enzyme system with CRISPR-like repeats
Mehgularity
kikokikokiko··on Brazil is having it's own "Lou Gehrig" moment [video]
Lito Souza is a brazilian influencer. He has a Youtube channel dedicated to aviation education, history and news, with 4 million subscribers. He's the most kind soul you can ever meet.

At the beginning of August, he started having difficulty controlling his left arm, and the doctors, at first, thought it could be a complication of his recent prostate cancer diagnosis. Unfortunately, last week it became confirmed that Lito was suffering from Creutzfeldt-Jakob disease.

CJD is a relatively obscure disease, and in Brazil, for the average Brazilian, it was pretty much a complete unknown ailment.

Now the whole country is in tears watching the developments. His wife, Mila, started a campaign trying to get Lito on any one of the clinical trials currently being made.

Specifically, there are 2 CJD clinical trials being done in Harvard at the moment:

@ionis_pharma — ION717 trial @broadinstitute — PRiSM trial

Everybody knows what the prognosis for prion diseases are. Mila knows it. Lito knows it. They are just asking for a chance at having hope. They only want to be allowed a compassionate use exemption.

I've seen more grown men cry those last few days down here in Brazil than I ever saw in my whole life. I never cried for a parasocial relationship before, but... if you are Brazilian, and you followed this guy, you would understand. The world will be worse the day Lito is not here with us anymore.

kikokikokiko··on uBlock Origin is giving up the fight to keep ads off Facebook
And some people appearing like flesh exposed monsters with ping pong balls for eyes
kikokikokiko··on Crime Pays but Botany Doesn't
Well, he wasnt very good at conveying his idea then. I also stopped reading at that point. Fuck anyone that holds this idiotic beliefs.
kikokikokiko··on Crime Pays but Botany Doesn't
Same here, I stopped reading right when he said this idiotic "guy from 300 years ago - when science as we know it basically only existed within the realm of white european culture" didnt thought about the rest of the world BS
kikokikokiko··on OpenAI's claimed disproof of Connes' Rigidity Conjecture is invalid [pdf]
These AI generated proofs have something akin to the quantum algorithms that can generate a response that would take 1 billion years of processing to finish on a classical computer. How do you test them to see if the result was correct?
kikokikokiko··on 'Backrooms' Stuns with $81M Debut
I would rather go watch Weekend at Bernie's for the 100th time.
kikokikokiko··on What Is a Dickover?
Yandex is great. When you want to see news/sites/whatever that does not conform to what the western mainstream powers "accepts as acceptable", you can go to Yandex and you will find it there. When Google search went to shit some years ago I discovered Yandex and found out how much of the web was being deliberately kept away from my eyes. You need search engines from every major power broker in the world to get a full picture of what we arrogantly like to call "truth".
kikokikokiko··on All phones sold in the EU to have replaceable batteries from 2027
Bullshit. This was the reason the industry gave for why they were removing battery replaceability support. Everybody hated it when it was first introduced, and to this day I only buy phones which have easily accessible ways to put a new battery on when the day comes. Fuck this BS of "people wanted thinner phones".
kikokikokiko··on OpenAI's $852B valuation faces investor scrutiny amid strategy shift, FT reports
Falling knife or not, if you own an index fund, or if your 401k owns one, you're buying a piece of it at IPO prices. The exit scam is almost complete.
kikokikokiko··on Artemis II crew see first glimpse of far side of Moon [video]
HN is heavily populated by and biased towards left left leaning west coast IT adjacent people. But it still makes me wonder for how long can the US keep it's dominance on the world stage with so many people that think this way in positions of power on the arguably most important econonomic/social area from now on.
kikokikokiko··on Nightingale – open-source karaoke app that works with any song on your computer
Karafun is a paid service? I've seen their karaoke songs on Youtube for over a decade, I thought that was their business model.
kikokikokiko··on Are the Mysteries of Quantum Mechanics Beginning to Dissolve?
If everything is deterministic, i.e. determined, there's no free will, so you/I are just a NPC. I prefer to live in a universe where my conscious decisions matter, or at least can't be predicted beforehand.
kikokikokiko··on Are the Mysteries of Quantum Mechanics Beginning to Dissolve?
To me, the fact that quantum mechanics is intrinsically "random" and unknowable beforehand, is what makes living bearable in this universe as a sentient being. If we, two legged viruses that we are, could reach a level of understanding that could show the universe to be fully deterministic and every future state to be knowable given that you know the current states, then this human condition would be impossible to stand. I love the fact that we just can't predict the future. It's what makes existing be a good thing instead of a bad one.
kikokikokiko··on Review of 1984 by Isaac Asimov (1980)
Yep, no rational argument can be used to make you (or me) see the same movie.
kikokikokiko··on Review of 1984 by Isaac Asimov (1980)
These Minessota videos are classic examples of what Scott Adams used to call "two different movies being played on the same screen", in this case quite literally. From the point of view of a left leaning person, that movie shows a man being assassinated for no reason at all, nothing justify what happened. From the point of view of a right leaning person, Alex Pretti was actively interfering with law enforcement, and he entered a conflict situation while carrying a gun. If a cop is in the act of fighting you, and see a gun, you carry the risk of being shot, it's just reality. The right leaning person, just based on these facts, already reduces the charges from murder to manslaughter, max. Two movies on one screen, and there's NOTHING rational that can be said to change the mind of anyone. Everybody is watching the same damn screen, but the movies are completely different.
kikokikokiko··on Profession by Isaac Asimov (1957)
Go create something original instead of tryingto destroy the greatness "created by a white guy" in the past.
kikokikokiko··on Bringing Sexy Back. Internet surveillance has killed eroticism
Abnormal = non normal / non normative. Words have meaning. If for you it causes a bad reaction to it, you are the one that needs to deal with it. That's excatly the problem, normal people are tired of being called bad for seeing the world through normal, reasonable lenses. When a behavior does not follow the norm, it's abnormal.
kikokikokiko··on Bringing Sexy Back. Internet surveillance has killed eroticism
Yes, the analogy to the bell curve doesn't fit this use case very well, I didn't noticed it before. But the point still stands: non heterosexual behaviour is a tiny minority compared to the norm. So, abnormal is a perfectly good word to describe non-heterosexual behaviour. Once again, it doesn't make it bad per se. I just can't stand word police, which is just another facet of thought police.
kikokikokiko··on Bringing Sexy Back. Internet surveillance has killed eroticism
If something falls out of the center of the normal distribution, it's by definition abnormal. Once again, that doesn't make it bad per se. But trying to police perfectly good words just makes people become more antagonizing to the position you want to defend.
kikokikokiko··on Launch HN: Tweeks (YC W25) – Browser extension to deshittify the web
I used to assume that the average Joe would be amazed at the way my Youtube/Facebook/whatever looks and works, with no ads and with a lot of annoyances removed. Then I saw, more than once, people complaining that THE ADS were gone, and then I gave up. The average of the whole population of humans is a very dumbed down version of what I always imagined the average would be.
kikokikokiko··on Jack Kerouac, Malcolm Cowley, and the difficult birth of On the Road
Not a "guy novel" at all. I read it around 20 and just thought it was a waste of time, nothing happened, just wandering around aimlessly like 90% of my buddies on their teenage years. The whole beat movement was just style over substance, pages and pages of nothing.
kikokikokiko··on Old Stockholm Telephone Tower
I believe the concept of multiplexing made the tower obsolete, orher than the subterranean cables of course.
kikokikokiko··on Betty Crocker broke recipes by shrinking boxes
The most infuriating case of shrinkflation I've encontered yet is abot the "Oreo" style cookies, that were used to be sold on packages where each cookie was stacked on top of another, "laying flat". Over time, rhe packages started getting lighter, the cookies itself started getring smaller etc. Then, a couple years ago, those packages started having the cookies "side by side", instead of laying one on top of the other... I refuse to buy any brand that uses these types of shenanigans. Fuck shrinkflation.
kikokikokiko··on Everything from 1991 Radio Shack ad I now do with my phone (2014)
For fixed radars, at least down here in Brazil, RadarBot is a lot better than Waze. For cops on the side of the road, maybe Waze can be better. RadarBot updates it's list of fixed spees cameras really fast.
kikokikokiko··on FreeDroidWarn
All banks in Brazil now use the Google Play Integrity api. I've been on rooted phones for almost 15 years, and I'll never not main a rooted phone. But for a couple years now, I have to keep a separate phone just to be able to use tha f*cking banks.
kikokikokiko··on FreeDroidWarn
If it was 2023 I would say someone just vibecoded a trivial android piece of code. But nowadays Android studio comes with Gemini agent integrated, and I doubt it would produce such terrible redundancy on a code so simple.
kikokikokiko··on FreeDroidWarn
every single Brazilian bank for instance
kikokikokiko··on FreeDroidWarn
A little bit overkill to use a dependency to just show a dialog. I agree that Google ia making Android less and less free with every new release, but show a damn dialog, no need to use this.
kikokikokiko··on Beyond Meat fights for survival
Like the one the aztecs regularly unleashed upon their neighbors? Or any pre-colonial tribe in the Americas or Africa (in this case up until this day really). What did the Romans brought us really?
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