jostmey

I'm surprised there isn't more effort to create hybrids in reverse--an electric car with optional gas generator. The gas generator could run at constant speed, never changing RMP, while the battery handles constant changes in acceleration. The idea is not mine. I've heard about it in China

The tax system in Texas is a better system. Sure, Texas has lots of problems. That doesn't mean there is nothing to learn from Texas.

I live in Texas. I don't like the restrictive laws. Texas could learn a lot for California, just not in the areas of taxation

And why won’t the frontier models continue to become better? The open models are getting better but so are the frontier models. The frontier models might remain in a constant race to remain ahead

I cancelled my ChatGPT account for the restrictions placed on my account, inappropriately flagging about 10% of my queries as unsafe (I was writing grants in immunology). I haven't looked back. I will do the same if with Claude if Anthropic doesn't reverse course soon. What could I use instead? I find Grok very powerful and useful. Also, Google's Gemini, while also have some of the same restrictions, were at least sensible and not blindly blocking my prompts. So Grok and Gemini may be my go to AI's going forward

The real issue isn’t finding therapies but getting them tested in clinical trials

15000 milliseconds! Makes me laugh. I've had the same issue! Usually happens in the morning

I’ve noticed regression and it’s performance too

I am assuming the proposal is to knockout the gene Lim1, which in other animals, creates a brainless phenotype. You won't be able to swap a brain into this headless body (assuming it can fully develop), but this approach could be used for medical research and potentially solve the problem of organ donors, assuming it is ethical

Also, just because Lem1 creates a headless mouse doesn't mean it will do the same in Humans. But I suppose that's what the primate testing will reveal

Claude is only as good as the prompts it’s given

It could still be more fair than no standardized testing

I personally find Claude the best at coding, but it’s usefulness doesn’t seem to extend to scientific research and writing

I noticed how ChatGPT got progressively worse at helping me with my research. I gave up on ChatGPT 5 and just switched Grok and Gemini. I couldn’t be happier that I switched.

The old chat gpt models scanning the nih pub med repositories with proper prompting (e.g. …backed by randomized control trial data) was an amazing health care tool. The stripped down cheaper versions today are junk and I’ve had to start relying on grok :-( I’m not convinced OpenAI can make this work

Makes sense to me! And poor diet is probably one of the biggest problems in the United States

The single reason I use apple maps instead of google maps is because of the lack of ads. For me, it is really the only competitive advantage offered by apple maps

Phone and laptop batteries probably make up a tiny fraction of the battery market. My EV battery is almost 5000 times the size of my iphone.

Sodium batteries, if the technology works, would replace EV batteries and provide support to the electrical grid, and would be purchased at thousands of times the volume of iphone ad laptop batteries

A small bush fire is not supposed to cause 60 billion in damage. Also, innocent until proven guilty. The evidence against the guy seems weak… like generating images on ChatGPT

But what if AI succeeds and it’s the rest of the economy that implodes? Long-term, I’m sure AI will lead to massive productivity gains. Short-term, I think it’s going to be chaotic. I don't know which will implode, AI or repetitive white collar work or something else

Rejected is not the same as suspended. Top scientist and mathematicians sometimes submit grants that are rejected. But suspended is another matter

I wonder how much variability there is in the product from batch-to-batch. Could one batch be producing unwanted by products at a much higher quantity than another batch?

Yeah, that is the big question here... how much is being produced. Also, how variable is the product from batch to batch? Could one batch be producing byproducts at much higher quantities than another batch?

According to the article as I understand it, the bacteria in question directly produces formate, the suspected culprit behind the vision loss. Ethanol being produced by the bacteria is not the relevant information here

I wonder if this will be an ozempic moment catering to men's physique

Texas also has installed large amounts of battery capacity, often providing over 5% of the total grid power during sunset hours

I’ve only peer reviewed a few papers. I’ve submitted my share of papers for review

This is my academic profile https://scholar.google.com/citations?user=bxn78bkAAAAJ&hl=en

This only addresses a small part of the problem with peer-review. The real problem is that peer reviewers can’t possibly replicate the study, and so are forced to look for inconsistencies in the papers. If the paper doesn’t fit what is expected, it will often be rejected. This can also lead to self-reinforcing views that ignore contrarian data. Also, the data can be made up, and if it makes sense to the reviewers, it is generally not questioned

Agreeed. My last uber and Lyft rides were an unpleasant experience of late pickups, cancelled pickups, and old rickety rides. I use the train over uber and lyft

This should only act as a clue into driving weight loss. Depleting of cysteine is severe. It would be depriving a team from writing html and discovery the code runs faster… very drastic imposition

For every person that went through these elite schools, they must have rejected five or more other people. These schools pride themselves on turning people away. Perhaps, they have far more enemies than friends, explaining their seeming lack of influence in this situation

No, but investment banks were bailed out by the federal government at the taxpayer’s expense while the lower classes saw nothing