johnwyles

I too am an advocate but willing to bet you some scratch that the incidence of grief, harm, or violence from someone tripping on mushrooms versus a tee-totalling sober population is lower. You went directly to the most formidable source for reporting trips and they even break it down by bad experiences vs good vs etc. so of course you're going to find some stories that exist.

Are we speculating that the patent filed is on the process for production? Any references here?

did you read the article completely? there are 9 critics that worked with them, 6 ceased doing so. the company formed and closed it's non-profit venture and they are using typical pharma tactics, creating patents around it. spin is one thing but those facts do tell a story on it's own.

> These experts are further troubled by the company’s business structure: Having first registered as a charity, Goldsmith and Malievskaia set up a for-profit corporation working towards the same ends just one year later, and closed their non-profit less than two years after that. And all 9 of these critics charge that Compass Pathways has relied on conventional pharmaceutical-industry tactics that could help them dominate the field, including blocking potential rivals’ ability to purchase drugs, filing an application for a manufacturing patent, and requiring contracts that give Compass power over academics’ research and are restrictive even by pharmaceutical-industry standards.

I'm not saying you're wrong per se but what evidence do you have that there are no beneficial analogs and triggers for similar biochemical pathways that perhaps are not marked by a substantial or profound classically psychedelic experience?

> If you have no clear idea how your driving software works, how are you going to make sure this doesn't happen?

A lot of people don't know how typing "www.google.com" into their browser works but DNS "just works" for them. There is software in nearly every part of our lives that could systemically go wrong in catastrophic ways - we do our best to plan and prevent them.

> People have common sense, variability and adaptive learning to prevent things like that. Moreover, our traffic system, our cars and our driver education have been co-evolving for safety for the last 100 years. (Heck, some of it started with horses and carriages.) The complexity and size of the system have been gradually scaled up for just as long, and it's designed and refined to be used by humans.

Isn't that incredible? The complexity goes up: we adapt. As self-driving cars are introduced we adapt and evolve and incorporate these changes in technology, the driving "environment", security, safety measures, and laws and regulations.

> Traffic system isn't a board game.

I didn't see any efforts at self-driving vehicles just say "ahhhh! this driving stuff is so easy!" Of course it comes with huge difficulties, an enormous amount of complexity, a baffling amount of data, a ton of edge cases, and now a wealth of tribal knowledge on the subject.

When considering these things think of the systemic benefits as well. There was a story on the Google self-driving cars in Mountain View not taking a turn when the passengers of the car expected it would. Turns out that the IR sensors on the vehicle saw that a jogger behind a wall of hedges was about to enter the intersection to cross while jogging. Systemically implementing that change across a fleet of cars would then save untold numbers of injuries or lives.

We adapt.

On that topic Haskell is soooooooooo much more readable than clojure to me

had the same epiphany driving from CA to WA through OR. Oregon allows logging to clear-cut - meaning they don't pluck 1 tree among 5 to cut but instead just lop entire mountainsides down like someone getting a buzz cut.

To be fair a lot of West Texas if you're not looking at a bunch of windmills you're looking at about as many derricks - neither are very pleasing to the eye.

Native Texan. Austin and not Austin all my life. Never heard "on balance". Some family in the industry. They know they are seeing the last boom before the bust. I was surprised to hear so few of the wind over there is with any of the big energy companies.

> One almost-exception: voluntary treatment involving the mother (mostly by the mother) has only a slight negative effect. Father does not seem to matter if they're part of treatment. Still does not have a positive effect though. (Absense of a father has a strong negative effect though. I would love to see studies on if you see the same with mothers where the father is the primary caregiver)

Can you clarify #4? What "treatment" are you referring to? Chemical dependency? Treatment in child services?

Yeah, that got me too. I was looking for the butterfly with a cowboy hat sitting on a bail of hay with a "Butterfly Saloon" sign behind them.

I remember finding this project years ago and it is indeed much more flushed out than when I checked it out then. However, and I recognize this is begging disdain from Linux purists, I wonder if their are any React projects with a similar goal, target audience, or set of features/games? I feel like there would a more vibrant contributing community releasing a richer set of unforeseen features, challenges, games, etc. I am not a huge fan of React, electron, etc versus native apps personally myself but I cannot dismiss the very active and large community and for a project like this I feel like there could be a great benefit. I suppose when someone writes most of these apps for kids they are charging for it in the App Store and that is where a project like I am envisioning quickly falls short. Thoughts?

n00b question: are the GPS signals used by drones and commercial airliners the same? I know the military have their own special class of GPS.

Isn't it funny the Palm Pre was in some sense what Electron apps have become? Just an anecdote - I understand all the differences between them but I didn't even think at the time the Pre came out that it was "ahead of it's time" but I suppose it was - then again there was also the iPhone that killed it as well.

I will echo this too. I think Go has helped usher in the sensible concept BDD and of microservices to the forefront and the do one thing do it well approach. Versus monolithic applications instead you have a lot of digestible standalone services comprising the overall application and Go excels in this.

DDoS of brogrammers and financially obsessed man-children. I think he nailed it. However the content in his pages is very lightweight and hosted in AWS it looks like so maybe that referrer logic pre-dates him hosting it and the DNA Lounge website there and... also because what he has to say is certifiably true. Good laugh.

tl;dr CaaS doesn't orchestrate the underlying infrastructure whereas k8s primary purpose is to create a cloud agnostic way to orchestrate containers and the infrastructure that they run on.

I can hear your snarkiness through this comment because we are all in the same industry. However, the average NYT reader probably hadn't seen or heard from Microsoft in a while to know that Azure is a big deal which is who this article was written for. Timely because of the stock price between them and Apple who we read not long ago were on course to be the first trillion dollar company.

Exactly. Look at the computational power we have thrown into figuring out just how a protein folds for example. I worked in a lab where we used a lot of inference in the 2D structure of RNA over a decade ago after the 23s and 16s ribosomes tertiary structures were resolved. I was simply working with 70-120 base-pair tRNAs and that alone was computationally complex using a known model to compare against! We have still but scratched the surface.

Building a core cell always intrigued me as an undergraduate and I was often interested in the bare minimum (DNA-wise) lab manufactured bacterial strains that were used in experiments.

"nixos" might save some trouble?

I've sometimes struggled with this problem with "go" (=> "golang")

naming big projects something common should be a no-no and it's a pet peeve for most of everyone. for something with a very limited scope it's probably less annoying

I clicked to the comments to find this very explanation. Albeit I know next to zero of the industry or complicated financial structures surrounding the topic that even I as a layman felt it grossly sensationalist.

I'm here. I moved from Austin (call me crazy). I haven't seen a slowdown in recruiter spam since I've arrived.

35 = corpus christi

I'd put this at pretty unlikely - I suspect the early experiment was never expected to take off anywhere close to what it has and so the foresight of doing this probably overlooked.

I'd bet 0.05 BTC he is over 40.

someone above posted this: https://github.com/calmh/syncthing/blob/master/protocol/PROT...

Aside: I was wondering this about Bittorrent Sync as well - would you happen to know?

Everest is kinda getting ridiculous. If you do any reading or watching on treks up the mountain you know the only way 90+% of these "mountaineers" get up to the summit is because of the hard work and ascents of sherpas. I'm happy to hear about the strike and hope it turns away the popularization of something I think isn't as novel as we make it out to be. Why not explore space instead? My $0.02...

Also keep in mind that Formula E debuts this year; it will be the sport we all eventually follow (not sure how I feel about the passing cars sounding more like aircraft than cars): http://www.fiaformulae.com/

If they do not now they could, in the future, retroactively find you and tax you for gains on BTC since the ledger is public and traceable. If this really concerns you I suggest you read-up on Bitcoin Mixers / Tumblers - but be warned these services could be dubious and take your BTC for their own!