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jeremiahbuckley

61 karma · joined December 24, 2021

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jeremiahbuckley··on HBO Documentary Suggests Bitcoin Creator Satoshi Nakamoto Is Peter Todd
Would be a pretty amusing black comedy. They kidnap the potential Satoshi, who is actually Satoshi but they’re not sure. [hijinx added here]. Then in the process of torturing him, they accidentally kill him before he reveals the password. And then it’s confirmed he’s who they wanted.
jeremiahbuckley··on London Tube map redesigned by Essex lecturer goes viral
Thank you. TFA links to the map that was part of the Google/Samsung ad, but not to the map that apparently everyone is excited about and is the topic of the story. Ridiculously petty editorial choice for information hiding.
jeremiahbuckley··on Delta to Seek Damages from CrowdStrike
Best answer I can guess: because it's easy and cheap to set up, and the dev team involved was moved to another project years ago.

Windows is dominant for UIs because of a long history of having drivers for all the various peripherals which eases hw procurement issues. Sure that advantage went away long ago but the momentum takes a long time to die out. The brains with the expertise know how to do it on Windows. Combine that with the fact that Windows UI is not something you have to train new hires on and it makes business sense that all the user-facing interfaces ended up Windows applications. Sure, over time they should be migrated to containerized web UIs, but there's a lot of work to be done. Updating the flight arrival display isn't mission critical; it's at the end of the backlog.

I believe I heard one thing that got screwed up was a crew-scheduler product. Like: they couldn't check in crews or get their schedules written in so a system (presumably something on a mainframe) could work out where all the people needed to be at what times. Much more mission critical! The central big brain was (probably) not Windows, but those user inputs at the end were enough to screw up the whole business process.

jeremiahbuckley··on Delta to Seek Damages from CrowdStrike
"to begin with" is expecting miracles we don't have today. Delta has been around forever and presumably runs a lot of critical stuff was written in the 90s, or (hopefully not by now) even the 60s. And, as cool as Linux is as an OS, many smart people program in C#/MSFT-stack, and you don't want to remove them from a talent search if you're Delta and need 1000s of developers. And this CrowdStrike thing wouldn't have been mitigated by running a Windows App in a container, it would have killed the Windows OS supporting the container (I'm pretty sure...).

"Premature optimization is the root of all evil" is a common architecture guideline. Well, in a way Delta (and any company 30+ years old) optimized all their business processes using old coding standards. Now they have to effectively change the oil while the car is driving down the highway. Whoever figures out how to get AI to assist in this will make the first AI fortune.

jeremiahbuckley··on Psilocybin desynchronizes the human brain
I appreciate the pushback on this process, it made me think.

I actually asked the LLM for supporting or refuting sources. I didn’t think I was cherry picking. Looking at its response… maybe CharGPT didn’t pick up on the “refuting” detail, or maybe observationist was correct. So maybe next time a prompt “find supporting” and another prompt “find refuting” would be useful to ensure coverage of both sides.

My value add in the human+AI workflow was to check the links. They seem high quality and directly applicable to statements made. I took pressure off observationist to go find directly applicable links (and I saved time by not googling for each separate fact). That being said, I probably didn’t need to requote ChatGPT in full. I liked the full answer because it assured me ChatGPT was responding on each claim but the important thing was the links. So, more efficiency was possible in my yc comment.

jeremiahbuckley··on Psilocybin desynchronizes the human brain
A user named observationist made a response to this post, but they responded to a troll, whose comment was nuked which removed their very valuable comment (I was responding to them at the time so I happened to have both in cache).

observationist https://news.ycombinator.com/user?id=observationist original comment:

Around 1% of people have schizophrenia. This holds over a lifetime - there's a structural, unavoidable component to the person's neural wiring or physiology that will result in a schizophrenic break. Prior to the break, they may seem more or less normal, but after, they will experience deficits in cognition and perception, and may have significant barriers to living a normal life. Schizophrenics, as a rule, will have a psychotic break before they turn 45. Psychoactive substances, and high doses of psychedelics, will trigger breaks from reality earlier than they might otherwise happen. Stress, caffeine, trauma, or significant excitement can also be triggers, but psychedelic drug trips are a reliable trigger, and in conjunction with other effects, can spiral a "bad trip" into a much worse trauma.

Another 3 to 4% of the population have significant mental disorders, ranging from those we know, to those we can observe but don't have a good diagnostic criteria for. In these cases, it can be very detrimental to use psychoactive substances generally, and psychedelics in particular.

It's crucial to visit with a doctor to rule out the likelihood that you're in the roughly one in twenty people that might have a significant negative reaction to psychedelics. Some of the people in that camp might be safe from harm later in life. I know a person with significant family history of schizophrenia and earlier life indicators he was at risk, who then started using mushrooms in his 50s and seems very stable. He talked things over with his doctors before deciding to take the risk - apparently after you turn 45 it's incredibly rare, even with significant trauma and stressors, for schizophrenic breaks to occur, so if that's your main threat, it might be safe to engage in psychedelics when you're older.

If you're not in the high risk camp, you should still have at least one frank discussion with your doctor about pitfalls, and do a metric ton of personal research about any substance you intend to use. It can be a profound and wonderful departure from the norm, or a mildly unpleasant experience, or a stressful confrontation with your inner demons, depending on the dose and preparation.

my response:

Thank you for this. I thought this was a very informative comment; I am worried about schizophrenia as a disease that might impact my kids. I wanted to ask you for more information, but that is a burden, so I asked ChatGPT instead so at least you wouldn't have to go find links. If you have Other reading besides what is below I would be happy to hear about it.

Here is it's response from ChatGPT (Claude couldn't provide links). My contribution is that I checked the links and skimmed them to see if they supported the statement. They are repetitive (there are only 7 articles linked actually), but they generally support your comment. Of note the PLOS article does not support your comment, and it seems that it doesn't support what ChatGPT says (maybe I misunderstood when skimming it). The stuff in parens below (Looks Like This), was a link in ChatGPT, but the links didn't copy-paste, so I'm going to put all the articles at the top here:

https://www.nature.com/articles/s41380-023-02138-4

https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12...

https://www.who.int/news-room/fact-sheets/detail/schizophren...

https://www.nimh.nih.gov/health/statistics/schizophrenia

https://www.psychiatrictimes.com/view/drug-psychosis-may-pul...

https://psychedelics.berkeley.edu/qa/understanding-your-risk...

https://journals.plos.org/plosone/article?id=10.1371/journal...

The comment you saw online contains some accurate points but also could benefit from additional context and nuance based on available research.

1. Prevalence and Risk Factors of Schizophrenia:

- The lifetime prevalence of schizophrenia is approximately 0.3% to 0.7% globally, which supports the 1% figure as an upper bound (Nature) (BioMed Central) (World Health Organization (WHO)) .

- Schizophrenia typically emerges in late adolescence to early thirties, with men often experiencing onset earlier than women (National Institute of Mental Health) (World Health Organization (WHO)) .

- Factors such as genetic predisposition, prenatal exposures, and psychosocial stressors contribute to the risk of developing schizophrenia (National Institute of Mental Health) (World Health Organization (WHO)) .

2. Triggers for Psychotic Breaks:

- The statement that high doses of psychedelics can trigger psychotic breaks in predisposed individuals is supported by evidence. Drug-induced psychosis, particularly from hallucinogens and cannabis, can lead to schizophrenia in some cases (Psychiatric Times) .

- Other triggers include stress, trauma, and significant life changes, which can exacerbate underlying vulnerabilities (Berkeley Psychedelics) .

3. Impact of Psychedelics on Mental Health:

- Psychedelics can pose significant risks for individuals with a family history of schizophrenia or other major mental health disorders. It is crucial for these individuals to consult healthcare professionals before considering psychedelic use (Berkeley Psychedelics) .

- Research has shown that about 25% of those with substance-induced psychosis may transition to schizophrenia, with the type of substance being a significant predictor of this transition (Psychiatric Times) .

4. General Mental Health Considerations:

- Around 3-4% of the population may experience significant mental disorders other than schizophrenia. For these individuals, the use of psychoactive substances, including psychedelics, can be particularly detrimental (PLOS) . [NOTE: This seems to be an error from ChatGPT, this PLOS article doesn't seem to support this conclusion. As I haven't done personal work on this yet, I don't know whether the statement is supported by other research.]

- Mental health evaluation and professional consultation are recommended before the use of psychedelics to identify potential risks and ensure safety (Berkeley Psychedelics) .

5. Later-Life Considerations:

- The risk of new-onset schizophrenia after the age of 45 is indeed rare, which suggests that older individuals may have a lower risk of experiencing a first psychotic episode triggered by psychedelics (Berkeley Psychedelics) .

For further reading and to deepen your understanding, you may refer to sources like the National Institute of Mental Health (NIMH), the World Health Organization (WHO), and recent research studies on the global burden and risk factors of schizophrenia (National Institute of Mental Health) (World Health Organization (WHO)) (Nature) . Additionally, the Berkeley Center for the Science of Psychedelics (BCSP) provides detailed information on the safety and risks associated with psychedelic use (Berkeley Psychedelics) .

jeremiahbuckley··on Psilocybin desynchronizes the human brain
Thank you for this. I thought this was a very informative comment; I am worried about schizophrenia as a disease that might impact my kids. I wanted to ask you for more information, but that is a burden, so I asked ChatGPT instead so at least you wouldn't have to go find links. If you have Other reading besides what is below I would be happy to hear about it.

Here is it's response from ChatGPT (Claude couldn't provide links). My contribution is that I checked the links and skimmed them to see if they supported the statement. They are repetitive (there are only 7 articles linked actually), but they generally support your comment. Of note the PLOS article does not support your comment, and it seems that it doesn't support what ChatGPT says (maybe I misunderstood when skimming it). The stuff in parens below (Looks Like This), was a link in ChatGPT, but the links didn't copy-paste, so I'm going to put all the articles at the top here:

https://www.nature.com/articles/s41380-023-02138-4 https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12... https://www.who.int/news-room/fact-sheets/detail/schizophren... https://www.nimh.nih.gov/health/statistics/schizophrenia https://www.psychiatrictimes.com/view/drug-psychosis-may-pul... https://psychedelics.berkeley.edu/qa/understanding-your-risk... https://journals.plos.org/plosone/article?id=10.1371/journal...

The comment you saw online contains some accurate points but also could benefit from additional context and nuance based on available research.

1. Prevalence and Risk Factors of Schizophrenia:

- The lifetime prevalence of schizophrenia is approximately 0.3% to 0.7% globally, which supports the 1% figure as an upper bound (Nature) (BioMed Central) (World Health Organization (WHO)) . - Schizophrenia typically emerges in late adolescence to early thirties, with men often experiencing onset earlier than women (National Institute of Mental Health) (World Health Organization (WHO)) . - Factors such as genetic predisposition, prenatal exposures, and psychosocial stressors contribute to the risk of developing schizophrenia (National Institute of Mental Health) (World Health Organization (WHO)) .

2. Triggers for Psychotic Breaks:

- The statement that high doses of psychedelics can trigger psychotic breaks in predisposed individuals is supported by evidence. Drug-induced psychosis, particularly from hallucinogens and cannabis, can lead to schizophrenia in some cases (Psychiatric Times) . - Other triggers include stress, trauma, and significant life changes, which can exacerbate underlying vulnerabilities (Berkeley Psychedelics) .

3. Impact of Psychedelics on Mental Health:

- Psychedelics can pose significant risks for individuals with a family history of schizophrenia or other major mental health disorders. It is crucial for these individuals to consult healthcare professionals before considering psychedelic use (Berkeley Psychedelics) . - Research has shown that about 25% of those with substance-induced psychosis may transition to schizophrenia, with the type of substance being a significant predictor of this transition (Psychiatric Times) .

4. General Mental Health Considerations:

- Around 3-4% of the population may experience significant mental disorders other than schizophrenia. For these individuals, the use of psychoactive substances, including psychedelics, can be particularly detrimental (PLOS) . [NOTE: This seems to be an error from ChatGPT, this PLOS article doesn't seem to support this conclusion. As I haven't done personal work on this yet, I don't know whether the statement is supported by other research.] - Mental health evaluation and professional consultation are recommended before the use of psychedelics to identify potential risks and ensure safety (Berkeley Psychedelics) .

5. Later-Life Considerations:

- The risk of new-onset schizophrenia after the age of 45 is indeed rare, which suggests that older individuals may have a lower risk of experiencing a first psychotic episode triggered by psychedelics (Berkeley Psychedelics) .

For further reading and to deepen your understanding, you may refer to sources like the National Institute of Mental Health (NIMH), the World Health Organization (WHO), and recent research studies on the global burden and risk factors of schizophrenia (National Institute of Mental Health) (World Health Organization (WHO)) (Nature) . Additionally, the Berkeley Center for the Science of Psychedelics (BCSP) provides detailed information on the safety and risks associated with psychedelic use (Berkeley Psychedelics) .

jeremiahbuckley··on Ask HN: How has AI changed your learning methods?
>> you can use it to explore the thought processes of why someone might pick a particular set

The danger I see here, is that if you ask an LLM to explain the thought processes, it will never say “I don’t know”. It will instead describe some thought processes associated with coffee grinders. It may say something like “this grinder has fine grain controls that allow customizing the size of grind.” …which that particular grinder doesn’t have at all…but that’s a thing people write about when choosing grinders. The frustration is that 90% of the answer will be accurate, but somewhere in all the sentences is a hallucination, treated with the exact same authority as the rest of the answer.

It’s very difficult to QA that type of error.

jeremiahbuckley··on Arthur Whitney releases an open-source subset of K with MIT license
I absolutely got it wrong, thanks for the correction.
jeremiahbuckley··on Ask HN: What was your most humbling learning moment?
(I actually scanned the comment thread to look for this comic, I was going to add it but you beat me to it.)
jeremiahbuckley··on Ask HN: What was your most humbling learning moment?
I quote this all the time to people. There’s too much, we’re spread too thin. Ignorance shouldn’t be considered a big deal or a huge embarrassment. Not being ready to learn is a problem, but ignorance is sort of the default state now.
jeremiahbuckley··on Armor from Mycenaean Greece turns out to have been effective
Thank you! I particularly like the brief clip of an armored guy standing on a chariot strapped to a treadmill. It appears he is able to stand stoically while machines work underneath him. I have to assume it’s some sort of wind tunnel test and there’s a fan or something off camera left?
jeremiahbuckley··on Arthur Whitney releases an open-source subset of K with MIT license
They’ve been charging a that amount forever, it’s a crazy ask. But you’ll be happy to hear that the quoted price is about 80% off of the price in 2000, so take advantage of the discount. In 2000 it was $100K/month.
jeremiahbuckley··on Eye exercises for myopia prevention and control: comprehensive systematic review
I’ve heard this is important for young kids when eyes are developing. Once the weakness is built in, there’s not much t that can be done.

But I definitely recommend this to people I know with new babies. We do a bad job consciously recognizing the difference between indoor and outdoor light, but they’re orders of magnitude different in actual brightness.

jeremiahbuckley··on Apple apologizes for iPad 'Crush' ad that 'missed the mark'
It is really amazing the difference in emotional impact. Nicely done in super hi def! Thanks for this.
jeremiahbuckley··on Deaf girl is cured in world first gene therapy trial
This implies that birds don’t get eye cancer even though their lenses are different. I wonder what their protection is
jeremiahbuckley··on Opera for Beginners
YouTube is great for watching Opera, although you need the subscription to not be distracted by ads. But, after buying that one entry ticket: state sponsored arts are constantly putting up super high quality new recordings of Operas on YouTube. It’s got subtitles so it’s easy to follow along. Yes the video is high quality watch-a-play-being-performed, not a real movie experience. But it’s great for understanding the whole work.

Otello & Don Giovanni

https://youtu.be/qcuaN3jN29Q?si=KQAoKDKHVeDCSxmk

https://youtu.be/8wEMzWH52FA?si=S80Dc_ssXbCBXUtI

jeremiahbuckley··on Opera for Beginners
Thank you for this. Definitely interested in Janáček but I’d forgotten about him. I liked some of the Moravian Folk Songs, particularly the one named The Bench (the numbering seems to be confused JW V/2 No. 3 on some recordings?)
jeremiahbuckley··on Transgenic Golden Rice, once hailed as a dietary breakthrough
“You can't build a peaceful world on empty stomachs and human misery.” - Norman Bourlag
jeremiahbuckley··on How to Use JSON Path
There’s nothing thing wrong with that approach if you’re working with jsonpaths on the regular. It’s all about time management, I guess. With json, and xml, and probably yaml, there is this recurring long-term pattern of:

1. Creat tree-structure document format that is flexible enough to handle all use cases.

2. Write a ton of content in this format.

3. Have to figure out a query pattern to accurately retrieve good info out of these structures.

Generally, I feel we’ve become good at querying normalized table data. But—-and maybe it’s just me being stupid—-wending through tree-structured data is still tricky. And I recently discovered LLMs are great at solving for it, if you ask clearly.

jeremiahbuckley··on How to Use JSON Path
1. Create a mock json document that has the structure you are trying to query.

2. Ask [newest LLM] to write the proper json path to get to the element you want to reach.

jeremiahbuckley··on Feathers are one of evolution's cleverest inventions
Excited to anticipate next-gen airplanes with slotted wingtips and their vanes controlled by AI for optimal performance.
jeremiahbuckley··on eBPF Documentary
One of the big wins is not so much “build and run your own stuff” but there are very nice low-cost (in terms of compute) performance utilities built on eBPF

https://github.com/iovisor/bcc

There are so many utilities in that list; there’s a diagram midway down the readme which tries to help show their uses. bcc-tools should be available in any distro.

Also, Brendan Gregg does a ton of performance stuff that is worth knowing about if you check out his other work. Not eBPF only. Flame graphs are useful.

jeremiahbuckley··on Cystic fibrosis breakthrough has given patients a chance to live longer
Thanks for this. Very cool to read these types of stories.
jeremiahbuckley··on FDA clears first over-the-counter continuous glucose monitor
My view: I’m busy, I have a lot of things I’m trying to figure out. For example, All of my free time should be spent getting better at AI programming. Seemingly infinite horizon.

I could carefully track a half dozen signals to correlate consumption to effect, but if the effect is “I’m tired and don’t have much willpower”, that’s hard to remember to track. I just haven’t built up that habit; heck I’m having a hard time keeping up the habit of light exercise.

I have a cousin who was diagnosed with some stage of diabetes; got a continuous blood sugar monitor; ended up losing a ton of weight. I’m definitely in the market for this—something to make it easier for me. It’s undoubtedly healthier for me than mainlining wygovey, which is another option on the table.

jeremiahbuckley··on Private company landing on the moon today
Seems like laws against crossing state lines for a medical procedure wouldn't withstand a legal challenge because it involves out-of-state commerce. I'm not a lawyer, but that intervention seems to be aggressive and exactly the place courts/congress would step in. Also, in a scenario where it would does hold up, then CA/NY would start doing the same w/gun stuff. And then FL/TX would respond with something else against CA/NY. So... MAD should prevent states from being too aggressive in this area.

Again, my concern is trying to figure out the statistically best way to navigate the various political landscapes and future political possibilities. It just seems too focused on one particular area of risk. I wouldn't categorically close out a good company / good career just because of this risk. This seems like the right place to recommend a hedge.

jeremiahbuckley··on Private company landing on the moon today
Oh, yeah, can't help you there. I was thinking you were commenting as a person in a blue state worried about a red state political policy. There's blue vs red and then there's Europe vs US. A whole different order of magnitude. I mean all the same economic freedom vs policy concerns trade-offs still apply; but I'm well aware that there is a massive rift in risk comprehension going in both directions. The US is huge and the stuff you see on the news isn't happening where people with nice salaries live (I mean, statistically never, the news is not statistically accurate).

But I encountered a funny additional problem with that recently when talking to a European transplant which is: you need a car in the US. The US is huge and cheap and safe but you need a car. If you don't have a car you have to live within a subway system. Then it's not cheap/safe (pick one).

jeremiahbuckley··on Private company landing on the moon today
I’m confused about this from an economic standpoint. Assume you could put aside an additional $5k while living in these states, wouldn’t that provide a hedge for the medical needs of your daughter? If needed, you could then travel to a location that provides what you are concerned about. (Not to get hung up on “$5k”, you could substitute any arbitrary number for this cost-benefit judgement)

If move opened the possibility for a lucrative and rewarding career wouldn’t the trade off be worth it?

jeremiahbuckley··on Hi everyone yes, I left OpenAI yesterday
Similar experiences, but different conclusions.

1. With advanced math I feel I retain at the n-1 level. Unless I’m using it, it fades. That’s frustrating but I don’t think it’s the fault of the deliverer.

I do think working through problems has to be part of the practice, I’ve bought workbooks to have something to try to drive the knowledge into muscle memory. It still fades, but maybe not as much.

2. Calculus, in particular seems super unimportant to real life. Stats and Linear Algebra, somewhat similar in Math Level, seem much more applicable. I’m very happy to see Stats being offered in high school now as an alternative to Calculus. For Calculus, you almost need to learn 3-4 rules and someone says “trust me, just memorize these, don’t spend too much time on this.” And you would be able to live a happy productive life.

jeremiahbuckley··on Cloudflare defeats patent troll Sable at trial
I like this as a direction to push, even if there may be some details that are later discovered to require correction. Is any org pushing for this?
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