Your response is so elitist it makes me sick. With admittedly little knowledge of genetics, you are willing to claim genetics as an important factor? Women have also been making tools for hundreds of thousands of years and many women are just as passionate as you. Do you even have
any reason to make such a sexist claim as "most [women] lack this internal drive(almost an obsession) I've had since before I can remember"? Why does it even matter at what age someone first became interested in computers? I didn't know what binary, linux, or programming is until first semester of college. It doesn't matter at all now. Attitudes like yours alienate women who might be interested.
I get new music ideas from friends, I would never use this. What I want is a webapp where you type in a band name and it just plays that band, not pretending to have any idea what else I would like. If only that were legal.
The speech emphasizes making good choices, which has nothing to do with the quantity of choices of available. The billions of dollars, in the context of his speech, is a gift, while leaving a job and starting an online bookstore is one of the choices that defines his life.