I wish MyFitnessPal was a SPA in places so I could click checkboxes and paginate the food catalogue at the same time when adding food to my diary.
Nearly everywhere else, IMO, no. SPAs are absolutely harder to build and people start with them by default because everyone wants to be Facebook, which your average CRUD site is not. You can pull in those fancy javascript features as you need them, and hell, even embed React in the one part of your site that truly needs it. Which is what React begs people to do on their website, but apparently people read that and say to themselves "That message is probably for the plebeians building a Todo list app or something. I'M building Todo++ Enhanced, so I'll probably need 40 layers of abstraction and about a gig of dependences to implement a form."