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More like font-weight, since !important is binary and this is more of a gradient.

It's not really that simple.

Only two companies in the world succeeded, the French company Sanofi which also tried making a mRNA vaccine failed.

Among other things that purple region determines the "priority"/"intensity" of the whole sequence.

You want it as high as possible to make as much spike protein as possible.

It's proprietary information, mostly they try various possibilities until they find one with high expression.

They sequenced vaccine leftover remaining in used vials.

So reverse engineering basically.