With my limited experience in the field of it, 10 years at some isp's and a few startups. Its seems to me that ppl how score less in terms of "agreeableness" have a way of getting in to positions where they are allowed to act out on their "entrepreneurship", since its often recognised as a sign of good leadership. Positions lower then CEO, maybe CTO or even further down the ladder, "head of yadayada" reporting to C*O's. I've nothing solid to support this though. But I've seen ppl (and companies) having to pay high prices for having these entrepreneurs not doing what they're actually good at. Source: gut feeling.
Edit: I have some, not sure I'm the right guy to disclose though.