219 karma · joined March 6, 2020
You don’t make a planet of 8 billion people work without the trappings of civilization, good and bad. You certainly don’t make it work without commerce and freedom of speech.
RCT-Proven: GLP-1 Agonists, mTOR Modulation (Rapamycin), NMDA Modulators (Ketamine), Metformin.
Speculative/Limited Data: Senolytics, Hormones and Peptides, NAD+, Nootropics and Adaptogens.
Keep in mind that the absence of published RCTs does not mean an intervention is ineffective; it may just be proprietary knowledge. Plenty of rich, private labs out there doing that kind of work today.
GLP-1 Agonists, Senolytics, NMDA Modulators, Hormones and Peptides, NAD+ and mTOR Modulation, Nootropics and Adaptogens…
Forget weight loss. These people are going for immortality.
Of course it doesn’t…
A more pessimistic view might be: Musk’s businesses have technological advantages but are financially over-leveraged. Their present success relies on heavy government subsidies while their future success depends on complete privatization of government functions.
This isn’t the fault of medical professionals, but rather a system optimized for minimum risk and maximum billing.
For example, my adult son recently went through a bout of rectal bleeding. He sits a lot in his job and we assumed it was hemorrhoids.
It was a Saturday so rather than wait we met up at the local urgent care. They did an external exam and decided he needed to go to the ER. No, it couldn’t wait. We had to go right away.
So we went across the street to the ER and took up a bed for seven hours waiting for a CT scan and results. The CT scan showed no active bleeding or any other cause for concern.
At this point, it was 2AM. The ER doctor suggested we allow our son to be admitted so that they could accelerate a colonoscopy on Monday or Tuesday. Yes, that’s 2-3 days in a hospital room just so we could avoid outpatient delays.
Now, keep in mind, there are no other symptoms. He feels perfectly fine. The CT scan shows no active bleeding.
To us, admission seems like overkill. The doctor isn’t much help. They are mostly exhausted and also exasperated at “the state of health care in this country.” We try to be empathetic but more or less it feels like they are holding back.
So what to do? Well, my son made his own decision - we left. The next day, I called in a favor with a GI doc I know. We were able to get a colonoscopy 10 days later. Guess what? Internal hemorrhoids.
This is irritating enough, but what is even better is that we could have had that answer in 15 minutes if someone had pulled out an anoscope. Sure we’d likely need an colonoscopy as a follow-up but we could have been out of the system very quickly. We could have freed up that bed in the ER. Heck, we didn’t even need to be in the ER at all. Oh, and 10 days of needless worry would be gone.
I asked a hospitalist I know why no one thought to just have a peek. The answer? Oh, they definitely thought about it, but no one uses anoscopes these days. The preferred route is a colonoscopy. Why? Well, a colonoscopy is a better diagnostic tool, but frankly it also happens to allow for better billing.
And boy, oh boy is the billing good. For the hospital alone, we’ve got upwards of $6K in billing. Who knows what the colonoscopy will run. We have good insurance but to cover the deductible I’ll likely be out $2K.
Naturally, I’ve already called the hospital and asked them to conduct a billing review, which will be followed by a medical review. The result will likely be a claim by the hospital that all procedures were followed correctly, which is technically correct. They did it all by the book, wasted an enormous amount of time and money, and irritated all humans involved.
Anyway, this anecdotal story might explain why well-educated people are suspicious of modern medical practices (at least in the US).
FWIW, I’m in my mid-50s and I’ve not had a colonoscopy either, and I won’t be getting one. It isn’t that I don’t want to take care of myself but rather I can’t afford to actually know if I’m sick. In the end, squeezing a little extra life out isn’t worth the financial tradeoff for my family in the long run.
Wouldn’t publishers stand to gain more by locking down their content from third parties and creating their own shared distribution platforms (e.g. search engines, aggregators)? As it stands today, Alphabet and Meta make far more money selling actionable data to advertisers than anything else.