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beowulfey

2,095 karma · joined April 11, 2013

Postdoc, cellular neuroscience
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beowulfey··on Claude discovers a novel enzyme system with CRISPR-like repeats
We don't know how our own intelligence works, much less anything else's
beowulfey··on Wikimedia Foundation refuses union recognition, hires union-busting law firm
We just went through institution of a union at my employer for one type of employee. The organizers did exactly this, and as an observer/affected party it was a little coercive. But you know it has to be, because people always prefer the status quo. It takes a lot of work to unionize and it ultimately never felt forced because we all wanted it. But man, the pressure to sign and put your name down was high, and BECAUSE there were no protections, definitely unnerving.
beowulfey··on The Xteink X4 E-Ink Reader
I would love something as responsive as the Remarkable tablet in this form factor
beowulfey··on Mexican government unveils a prototype for a new homegrown, ultra-affordable EV
There is a market for smaller cars and trucks but its probably smaller than for other countries. We don't have the smaller roads/spaces associated with e.g. Europe. But for sure I would buy small cars or trucks first any day compared to the monsters on the road; there are few options though.
beowulfey··on Measles surge in Utah sparks fears US could undo decades of progress
There is active propaganda against scientists and institutions; and scientists are decent but not excellent communicators. They lost the communication war and now the general public is very distrusting of science.
beowulfey··on Google will pay SpaceX $920M per month for compute
Why the hell ARE they even valued that way?
beowulfey··on Retro-Tech Parenting
There's definitely something to this idea. Our toddler absolutely loves her Yoto player, which is kind of like a tiny Walkman with cards instead of tapes. It's new but has that same old-tech feeling, IMO. She loves to pick out her favorite "albums" (some of which are stories) and listen to them. We have them all where she can easily grab them and swap them out. Have definitely lost a few cards but they're cheap enough and they usually turn up again eventually, plus it helps teach her to keep her things organized (if you lose it... it's gone!).

We also got an old VCR for free, and pulled out all the VHS tapes from the parents' attics. Another great system for the kiddo. We have an assortment of tapes that she can choose from, and we let her pick the tape and insert it herself. I think the tactile feeling of selecting and starting it up is very satisfying.

Somewhere along the way we forgot the importance of touch in interfacing with technology. We are definitely starved for that sensation in the modern world.

beowulfey··on Peptides: where to begin?
Even if you test a batch once, do people who get testing done do testing on all batches?

The synthesis of peptides uses some NASTY chemicals. I would be worried about lax manufacturer policies leading to contamination, even if one batch passes. The costs of FDA certification are the effect of that protection.

But whatever, this is the same attitude that people have against owning insurance. It is hard to recognize the cost of risk.

beowulfey··on Peptides: where to begin?
Clinical trials are not looking for fundamental mechanisms, they are there to ensure an effect is strong enough to say a product should be sold for that purpose. Otherwise you end up with snake oil salesmen. Because how can you be sure you are even injecting the thing the sellers claim it is?

I would encourage everyone interested in peptides to read about the state of medical science before the establishment of the Pure Food and Drug Act of 1906.

beowulfey··on Ryugu asteroid samples contain all DNA and RNA building blocks
Causality was not the point. The point was to refute the seeding hypothesis, and because they found those molecules, the effort to falsify the hypothesis failed. Now we can move on to the next attempt to refute, which, as you say, might be to study whether molecules can survive conditions of reentry.

Experiments do not tell us that something IS a certain way; only the ways it is not.

beowulfey··on I guess I kinda get why people hate AI
LLMs talk like people; there is nothing wrong with this. It's perfectly fine to be nice to something even if it isn't human. It's why we don't go around kicking dogs for fun.

I understand why people don't act polite to LLMs, but honestly I think not thanking them will make people act more dickish to other humans.

beowulfey··on Fix the iOS keyboard before the timer hits zero or I'm switching back to Android
where did you hear this?
beowulfey··on We tasked Opus 4.6 using agent teams to build a C Compiler
Your first post specifically stated:

"I'm curious - do you have ANY idea what it costs to have humans write 100,000 lines of code???"

which any reasonable reading would take to mean "paid-by-line", which we all know doesn't happen. Otherwise, I could type out 30,000 lines of gibberish and take my fat paycheck.

beowulfey··on DHS keeps trying and failing to unmask anonymous ICE critics online
It is not possible to "dox" a public employee because that information is legally public information. Don't become a public employee if you want your job to be private.

see e.g. https://www.openpayrolls.com

beowulfey··on TikTok is now collecting more data about its users
Fully agree. Forums predate social media and are some of the oldest parts of the internet. And it's not quite socializing... it's more like, are you broadcasting and consuming content? Or discussing it?
beowulfey··on GPTZero finds 100 new hallucinations in NeurIPS 2025 accepted papers
As with anything, it is about trusting your tools. Who is culpable for such errors? In the days of human authors, the person writing the text is responsible for not making these errors. When AI does the writing, the person whose name is on the paper should still be responsible—but do they know that? Do they realize the responsibility they are shouldering when they use these AI tools? I think many times they do not; we implicitly trust the outputs of these tools, and the dangers of that are not made clear.
beowulfey··on Boeing knew of flaw in part linked to UPS plane crash, NTSB report says
They may have meant grounded, not decommissioned. DC-10s were grounded alongside the MD-11s.

https://www.flightglobal.com/safety/us-faa-broadens-md-11-gr...

beowulfey··on A closer look at a BGP anomaly in Venezuela
What is the purpose of saying this? It's being unnecessarily antagonistic towards a genuine sentiment. It's not like you are offering any solution either. Are you proposing nihilism, maybe?
beowulfey··on Rubio stages font coup: Times New Roman ousts Calibri
I would have thought the change to Calibri was simply because office uses it as the default font now
beowulfey··on Schizophrenia sufferer mistakes smart fridge ad for psychotic episode
Ah yes, a great point. We must protect the freedom to heap shit on other humans
beowulfey··on Micron Announces Exit from Crucial Consumer Business
California had Fry's until a few years ago. Once they went under it basically ended the local market.

I'd love to see more market-style parts locations a la Huaqiang or Akiahabara

beowulfey··on OpenAI needs to raise at least $207B by 2030
But that occurred with a new form of media that people now use in more of their time than back before Google. It implies AI is growth in time spent. I think the trend is more likely that AI will replace other media.
beowulfey··on Pixar: The Early Days A never-before-seen 1996 interview
If you visit Disneyland regularly, Snow White is just as popular for costumes as any other princess and has been for a long time!
beowulfey··on In a U.S. First, New Mexico Opens Doors to Free Child Care for All
It's not just about the economy, it is about freedom of choice. What does Max and Avery feel about their careers? Would they rather be working or watching kids? If one parent has to stay home, that might mean having to give up a good career.

No one should be forced to choose between a career and kids, unless the goal is falling birthrates.

beowulfey··on In a U.S. First, New Mexico Opens Doors to Free Child Care for All
It's not an intractable issue. It's just a matter of economics.
beowulfey··on The last-ever penny will be minted today in Philadelphia
You can do this with State taxes too, but I think your impression that people just ignore it is correct. A good example of this is gas prices. Gas in CA is 70c per gallon, vs about 25c per gallon in the Northeast. This gets baked into the price, and is way more expensive in CA, but people need to buy gas. So you just have to pay. And since it is everywhere in the state, most people don't notice the difference.
beowulfey··on First recording of a dying human brain shows waves similar to memory flashbacks (2022)
Without ethics, other motivations inevitably end up undermining any good intentions an experimenter may have. Ethics are the "laws" of science that constrain us for the sake of all. Your opinions here reflect a Libertarian bent, I bet.
beowulfey··on A worker fell into a nuclear reactor pool
Unless I'm misinterpreting what you mean, I believe if it was reflected in the hair in the immediate aftermath, it wouldn't reflect internal circulation because hair does not grow that fast. It would have been from exposure to the pool rather than any amount ingested.
beowulfey··on A laser pointer at 2B FPS [video]
A frame is by definition flexible in how many pixels tall or how many pixels wide it is, and there is nothing in the definition that says it can't be 1x1.
beowulfey··on 4Chan Lawyer publishes Ofcom correspondence
I'm sorry that you are not familiar with how laws work but it's kind of a big concept and I don't really have time now to teach it to you. I would recommend Wikipedia or perhaps ChatGPT to get started.
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