Hacker News Reader

archimedes237on CERN bids farewell to the LHC and enters Long Shutdown 3

Hopefully no sophons appear.

archimedes237on U.S. science is in chaos

It's closer to 70,000 years. If not, then explain the Australian Aborigines.

archimedes237on U.S. researchers face new restrictions on publishing with foreign collaborators

"a lot" must mean 99% either directly through grants or indirectly by the gov paying the universities directly.

archimedes237on Alberta to hold referendum on whether to remain in Canada

It is technically possible to separate legally, but there are so many intentional roadblocks that it is effectively impossible to do so.

archimedes237on AI has a multiplying effect on existing technical skills

I know someone who got AI to make a full minecraft bot gui that will put down waypoints for people to see and dig at and then do an in-game dig search (bot uses jsmacros) and they know zero coding.

archimedes237on How Mark Klein told the EFF about Room 641A [book excerpt]

Exactly. I love reading on this site . Written while im on the public bus.

archimedes237on Intelligence Evolved at Least Twice in Vertebrate Animals

It can if having non-dead grandparents gives an advantage before reproduction occurs. Could be why we live longer than most species too.

archimedes237on The Road Not Taken Is Guaranteed Minimum Income

The government doesn't do anything. It is the people that do. If the poor people all choose to live off UBI then who will be building these giant housing blocks since it isn't the rich people that build housing?

archimedes237on 'It's a Heist': Real Federal Auditors Are Horrified by Doge

A lot of people wouldn't be able to manage it personally if they had a 401k even if they had the best of intentions.

archimedes237on Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects

Note, I have access but this is not my field. I just asked ChatGPT your question after have it read the paper. This is what the response was:

Yes, the paper provides the 12-mer amino acid sequence of BRP: THRILRRLFNLC .

Regarding post-translational modifications, the BRP peptide was synthesized with a C-terminal amidation, which was critical for its bioactivity. The non-amidated version of BRP was inactive in vitro . Additionally, the paper mentions that the C-terminal cysteine (C12) was synthesized as a free thiol .

So, BRP is not just a simple peptide—it has a key post-translational modification (C-terminal amidation) that influences its function.