amy_petrik

>An unreliable computer treated as a god by a pre-information-age society sounds like a Star Trek episode. star trek, and twilight zone too

Also, people are usually like LOL it's just mRNA it goes away

But evidence does show it CAN go back to DNA with mechanisms familiar to anyone edgycated in molecular genetics - https://pubmed.ncbi.nlm.nih.gov/35723296/

Now, that particular study is in whatever cell line, highly dubious how it pertains to a human body, a few steps removed. But if you say "will you see this if you vaccinate 500 million times in 500 million people each with 500 trillion cells" - yea probably you would

>I guess the problem is a mismatch between detection capability and treatment capability?

the problem is you do the test for 7 billion people, say, 30 times over their life... 210000000000 tests. imagine how many false negatives and false positives, the cost of follow up testing only to find... false positive. the cost of telling someone they have cancer when they don't. the anger of telling someone they are free of cancer, only to find out they had it all along

this tech isn't that good, nowhere near it, more like a 1 in 100 or 10 in 100 rate of "being wrong". those numbers can get cheesed towards more false positives or false negatives.

as for grail, they tried to achieve this and printed OK numbers... ... .. but their test set was their training set. so the performance metrics went to shit when they rolled it out to production

it was mostly marketing "oooh altivec can do sooo many FP calculations that it has to be licensed as a deadly weapon". Same kinda marketing for MMX "if a programmer was an a MMX guru then basically you have a supercomputer bro"

That's all great but it was all awaiting a killer app to make it all worth it and reasonable, versus random programs rarely supporting it for a little boost.

And the name of that killer app, using these DSP type features? Local AI.

>Lime disease Ah yes, good old Lime Disease, named after the town it was invented in, "Lime, Connecticut", Abraham Lime 1898, former student of Koch's lab in Germany.

> build digital twins (for the rest of us) on which simulate all-round interventions based

Digital twins, what a freaking crock. Imagine claiming to simulate the biochemical pathways of a trillion cells and 3 billion basepairs and a gorillion chemicals and sequestration zones. Least they could do is take a little tissue and screw around with a patient-derived organoid. If someone made a digital twin that worked proper they'd be making a killing in pharma trials and drug development

>Injecting refuse "CO2" into the ground will contaminate our water supply;

That sounds crooked as hell, sorry to hear. Far as I am concerned, the only person who carbonates my family's water is ME and maybe coca cola. This twisted, corrupted government bureaucrats taking kickbacks to make my drinking water carbonated, the insult of it all.

the modern skin, you know, uncovered from the outside world. as opposed to the victorian skin which wise hidden away from dangerous UV light behind many layers of undergarments, hoop dresses, 5 piece suits, monocles, and so on

>How is Cloudflare a parasite?

>I never said they weren't bad.

>I don't understand the hostility.

It's known the community here doesn't like Cloudflare, and anyone who's been on the customer end of Cloudflare would tend to agree. In that context, if you truly are blind to seeing this, when you said, "how is Cloudflare a parasite" to a group not liking of cloudflare... ... it may land as saying something like "How is Hitler a bad guy?", which I hope is self-evident is saying he's a good guy contextually, of course you could troll it out and devil's advocate yourself that you were merely asking an innocent question.

the first equals is a boolean test, like "A=B, True or False", the second equals button is an evaluate mandate, like "2+2" -> = -> 4. Evil bit of code under the hood with the treplicate stack

1) there is no absolute good and evil, only politics and consequent propaganda

2) thy social media dark mirror hast found that thy politically polarizing content is thy most profitable content, and barring that, propaganda is also profitable by way of backchannel revenue.

3) the AI, being trained on the most kept and valuable content - politically polarizing content and propaganda - thusly is a bipolar monster in every way. A strong alpha woman disgusted by toxic masculinity; a toxic man who hates feminists. A pro-lifer. A pro-abortioner. Mexicans should live here and we have to learn Spanish. Mexicans should go home and should be speaking English. And so on.

TLDR there was never a lawful good, that's a LARP. The AI is always chaotic because the training set -is- chaos

here's the thing

If I flew to Japan, overstayed the visa, take a job under the table, just hang out living there... I would not be surprised that, should the government discover me, that I would naturally be deported.

I will be happy to let America be a place where people can waltz in here unannounced and live here and do whatever, have an anchor baby, get SNAP and WIC and medicaid and welfare to raise that anchor baby, that's cool.... provided that I can go have a Japan anchor baby, live there without any visa or immigration paperwork whatsoever, and enjoy the free healthcare. I don't mind if people coming in never learn english... provided I can go to France and rightfully expect to have the French bend a knee and instead learn English on my behalf.

Nobody is trying to stop the transitions, electric cars are a dog and for shit. Specifically the batteries, they're hyper-expensive, the range is for crap, and they need to be replaced every X years.

The left was idiotic to think dumping Peter's tax money to buy Paul's new e-car, then in other cases outright legally banning non-electric cars, was the way to achieve this. To me, it's as silly as if the government got the idea in its head that steam engine is the winner and starts incentivized steam engine cars, with a year 2030 all-steam-engine goal.

The way to overcome this so-called "entrenched interests" is clear as a bell, it's not some dramatic political struggle against forces old and evil. Electric cars are already in principle more powerful, simpler, and cheaper, than combustion engines, an amazing concept. Only issue is the battery. Government should have been, and should be, pumping money into developing a non-crappy battery, THEN when that's ready, there would be no need to incentivize people. The subsequent cars would be cheaper AND better. Let market forces decide, legislating what people ought to purchase is what is called a command and control economy and evidence shows that's bad

You are right to say something like this freaks people out and the media would be happy to publicize it - fear sells.

Consider the dude who went around NYC with a power saw in each hand -- https://nypost.com/2006/07/07/saw-maniac-in-subway-horror-sl...

Knowing people are capable of such things, I would not be surprised to find a syringe full of some nasties going around. The saving grace would be, unless they were a poison or bioweapons expert, it's unlikely they pushed in a particularly deadly dose before being kicked away, needles often push slower than one might think.

All that being said, whereas when most people "snap" in the US we see mass shooting, other weapons can be equally deadly and more horrific. In addition to use of common sense gun bannin- I mean gun control laws, we need also common sense syringe control and common sense handheld powersaw control laws

You think Iran is going to be bombed and then… not retaliate?

If war was a physical fight, that what the US has done is a smack to the face, whereas an invasion might be a swing of a samurai sword. So, what we're doing here is getting worked up that a face slapping contest will transform into a sword fight.

This, "false dichotomy" retaliate=war, or not retaliate is warping things here. Yes, Iran will probably retaliate, but more likely a smack to the face than a strike of the sword. It ain't war yet, right now it's just a slap & a tickle.

I think we need to define "decentralized" here

Google in and of itself is decentralized from an engineering perspective. There's no giga-computer in Mountain View that all search requests funnel though. It's a highly distributed system, much like the internet itself - just a distributed system that a single entity controls.

The issue isn't central or decentralized systems or engineering. It's centralized OWNERSHIP and CONTROL. That is the aspect that needs to get cracked open... what a monopoly is to a capitalism, is what this is to the internet.

>Science should ALWAYS be free to ask questions and explore them no matter how uncomfortable they sound. And this is a huge overreaction to how the left politicized science their way and continued to say that’s it not political.

Like when a google employee was free to ask questions as to whether it was that women don't like programming as much as men, and got immediately fired? Because of course the cause is sexism.

Like when James Watson had suggested intelligence was genetic, and if races differ genetically, so too may their intelligence... also fired from Stony Brook leadership. Because of course alleles that confer intelligence genetically are magically perfectly balanced in frequency across all races.

Not to pick on leftists for ruining careers, the right has done this to leftists as well - see David Bohm, a Pennsylvania native and at the time brilliant contemporary of Richard Feynman, who lived out his life in Brazil because McCarthyism got him.

Thing is, the left did politicize science, just read Nature: https://www.nature.com/collections/daficfhiff

Or you can read what you need to get a professorship: https://mitcommlab.mit.edu/eecs/commkit/faculty-application-...

DEI is essentially a commissar type system where one must pledge to the political officer allegiance to the cause, one where proletariat origins are favored over bourgeois. Trump's response is heavy handed but what is happening here is poisonous and insidious, insofar as outright hiring one demographic group over another is universally seen as evil, but hiding it behind a process of bureaucracy and good intentions somehow transforms it into virtuosity. DEI is basically a parasite that has infected many systems and hurt many people, it would be more elegant to simply remove the parasite, but Trump's tactic of taking a metaphorical flamethrower to the parasite and its host both will garner popular support given a lot of people have a bad taste from DEI.

it's a bit like rocket engines, training a big fat LLM is super duper expensive like a rocket and all else being equal, you'd like to get it right the first try. someone who has built a lot of rocket engines knows all the gotchas and where to look out for traps and gremlins, same for someone who has built a lot of giga sized LLMs

sourcee: beerfest (2006) ::

Barry Badrinath, down on his luck man-hooker: It's $10 for a BJ, $12 for an HJ, $15 for a ZJ... Landfill: [Interrupting] What's a ZJ? Barry Badrinath: If you have to ask, you can't afford it.

> "[Zuck] has mediocre talent"I read it as he not talented himself. Not about the talent he employs.

I know Zuck personally and this is one of the big understandings to do with him. If you adjust his selector switch (just below the 3rd rib-like component on the pseudo thorax) to "science and engineering", you'll find he's the most brilliant guy ever, like Data from Star Trek! But this mode consumes some CPU cycles normally spent on hu-man interactions so he can come off as awkward.

A year or two back we switched it to "JW" (Jack Welch) and a sticky-fingered unix programmer spilled diet mountain dew all over the switch, it's been stuck there ever sense, hence here we are, hence the reputation for no-talent. It's there we just have to figure out how to get that switch jarred loose.

leetcode will strengthen the youngblood programmer for competitive matters such as competitions or interviews

The universe... what a concept. You know, the universe is a little bit like the human hand. For example, you have Growmann's Center right here and then you have undiscovered worlds and and Sector 8 and up here is Tittleman's crest so you can kinda picture it's a little bit like a leaf or, well, it's not a bowl. The universe is beautiful. Put all the stars, the hundreds of stars that there are in the universe into a bag and put the inverse into a bag and all of a sudden they become, well, when i was a child there was thought to be 9 planets but there are now ninety planets you know the ultimate fate of the universe is so dark and mysterious that it generates butterflies in my stomach and that goes to tickles in my spine and that creates goose pimples and then that penetrates my mind and then the whole big bang explos - BWOOO BWOO BWOO BWOOO BWOOOOOOOOOOOOOO

In most of the US, and in urban areas in particular, absolutely E-bikes are king. In California or the bay area in particular, motorcycles are a major contender due to ability to take on highways at speed, but still able to cut through traffic (lane splitting i.e. cutting between cars is 100% legal, but only in California, and neither legal nor illegal in DC), not to mention more power and range generally. The big difference here however is parking. Squeezing a motorcycle between to parallel parked cars is still significantly easier than finding parking for a 4-wheeled vehicle, but with a bicycle one can practically park anywhere that the bicycle can be locked up (depending on common sense decisions of how mad a person would be if you lock to some fence, vs how long you will be parked there)

> But when I saw Java's syntax, I was like....this is not happening.

No, you're good, this is the natural reaction of basically all programmers except for those strange beasts known as Java programmers who believe verbosity and needlessly complex yet organized in a twisted sense is nirvana, in the same way the accountant sees the tax return as nirvana. Many other language enthusiasts such as C, python, or LISP, will also get a bad taste for Java. Of course there are other gnarly languages such as APL or SAS.

there is a small community of people that do indeed run this locally. typically on CPU/RAM (lots and lots of RAM), insofar as that's cheaper than GPU(s).

>They are driven by young, dumbass children or inbred rednecks who bought the libertarian/fascist line about needing to own some libs or the line about the government needing to get out of people's lives and let everyone do whatever they want.

americans are individualistic. you wont get very far by saying "do things this way I passionately believe in OR ELSE, you inbred redneck". they then do this to spite you "own the libs". better to say, "do things however you want, it's not for me to say how you live your life, but that would be cool if you did X because Y and I'm passionate about this because Z. both sides of the aisle are guilty of painfully enforcing their beliefs on the other.

> We were sure that a better product would win people over and lead to viral success. It didn’t. Things grew, but so slowly that we ran out of money after a few years before reaching break even.

Relevant apocrypha: https://www.youtube.com/watch?v=UFcb-XF1RPQ

> has to be done by something closer to the hubble telescope (pointed backwards). state of the art is about 2x diameter, with adaptive optics methodologies that avoid needing to polish a giga-mirror over several years

>This tilts the balance on the whole enough to maintain the health of the network. If you change these, you'd need to introduce other mechanisms to preserve the network incentives.

This is the real key point here. In the P2P wars, only bittorrent was the winner (though the old networks still live on and you can find interesting stuff in them...) - the timeless lesson is leeches need to be getting the short end of the stick, people who give back, the prize bonus. It's a fundamental characteristic of human nature here, tragedy of the common leech or something like that

it's a fascinating read however I believe most psychiatric disorders are traced not to the mitochondrion organelle, but rather, the midichlorians