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alexander_singh

33 karma · joined January 28, 2021

Second time healthcare founder, passionate about digital health and improving outcomes using clinical-grade, tech-driven solutions. Currently founder and CEO of Alfie (YC W22), providing precision chronic care management to patients who struggle with obesity.

Also learning to code and hack healthcare by writing the Healthtech Hacks blog: https://healthtechhacks.substack.com/

Feel free to reach out at alexander[at]joinalfie[dot]com

YC Badge: 0x3a767ED2D102b16e307Fbb9ADA1CdD91a02fF867

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alexander_singh··on Show HN: Automatically Generate Company Names with Available Domains
env variable error that I missed on the build, thanks for noticing! Just pushed a fix up for this and tested that it's live!
alexander_singh··on New York City is building a wall of oysters to fend off floods (2021)
I've volunteered a few times with the BOP and it's a really great experience. Would recommend if you're in NYC!

https://www.billionoysterproject.org/volunteer

alexander_singh··on Replace Medical Coders with 10 Lines of Code
Spent ~30 minutes this weekend building a POC for automated medical billing with openai. Accuracy is limited, but definitely shows the capability for applying LLMs in healthcare.
alexander_singh··on MIT scientists discover neurons that light up whenever we see images of food
Would be interesting to see the link between these neurons and the hormones that control hunger in our bodies. Perhaps there is a way to deactivate neural pathways when we see food, v. just targeting hormonal pathways with obesity-related medications.
alexander_singh··on Understanding gambling addiction (2012)
It would be interesting to see a Reframe-like company in the space of gambling addictions.
alexander_singh··on Ask HN: What HN post made you money?
Have you thought about updating this to do the same for Airtable?
alexander_singh··on Ask HN: What's the best biohack you've found?
I also had a severe back injury - using a full foam roller can overextend your back and cause further injury. My understanding is a half-circle can just provide some lumbar support if you don't have good lumbar support in your desk chair, etc. I've also been told to roll a towel up and use it for lumbar support or lying on.
alexander_singh··on Ask HN: What's the best biohack you've found?
I used to spend most of my time outside but have shifted to a sedentary indoor lifestyle for the most part. Definitely missing out on vitamin D.
alexander_singh··on Ask HN: Any weird tips for weight loss?
Weight gain and loss is much more about biology that "just eating less". There are significant genetic and metabolic factors that contribute to each individuals' appetite and ability to control that appetite.

The stigma around weight gain has been reliant on this argument of overeating for so long, while the research has indicated that there's a lot going on behind the scenes that has to be considered.

"obesity is innate, that weight regulation is not governed by a uniform tally of “calories in–calories out,” and to quote Jules Hirsch, that “there is a biochemical or basic biological element in what it is that we call `willpower.'”5 The views of many Americans notwithstanding, weight is clearly far from being entirely within an individual's control. Genetic predispositions, in tandem with the development of food environments that facilitate overeating and built environments requiring minimal energy expenditure, may help explain why so many Americans are obese today."

https://www.nejm.org/doi/full/10.1056/nejmp1400613

alexander_singh··on Ask HN: Any weird tips for weight loss?
As someone deeply involved in the weight loss space (CEO of Alfie, men's health starting with weight loss), I would not recommend biology "hacks" to lose additional weight. Hacks often result in a series of other physical and sometimes mental harm. The best ways to lose weight are dietary changes and exercise, in some cases combined with medication for individuals who have struggled to lose weight via lifestyle changes alone.

Additionally, weight is lost mainly as CO2 because of the metabolic processes that convert fat into energy and this process' byproducts ~(84% CO2 and 16% H2O). Additional O2 intake would not cause your body to burn more calories, and it's unlikely this strategy would result in passive weight loss.