adora

Potentially sending to China.

I emailed Sequencing.com asking what the difference was between them and Nebula Genomics and this is what they wrote back:

(1) Nebula is our laboratory partner, and they sequence with high-throughput MGI DNBSEQ-T7 DNA sequencing machines.

(2) They are our laboratory provider, but the product is not the same! The whole genome sequencing product sold by Nebula on their site is different from the Ultimate Genome Sequencing service we offer in some key ways. One big one is that our service includes more than $200 in DNA analysis apps and reports (such as the Healthcare Pro report designed for healthcare providers and the Rare Disease Screen that analyzes thousands of rare diseases).

The biggest difference, however, is in the processing of the raw genetic data into data files that you can then use to get health insights. We have enhanced processing for these kits that is able to create insights not available from Nebula directly, including enhanced raw data processing through two special bioinformatics pipelines that provide comprehensive data and analysis of structural variations, copy number variations, and mitochondrial heteroplasmy. Both Telomere Length and HLA Typing are coming soon and will be retroactively added to all past purchases of our Ultimate Genome Sequencing service.

This is all fed into our One Genome technology, which allows you to do analysis in ways that you can't do anywhere else. This technology takes all of your genetic data and turns it into an enhanced virtual genome. This advantage of this is that you can run analysis on everything all at once, where in some other cases you might have separate files that can't be analyzed simultaneously.

The long and short of it is that it takes a lot of processing to turn raw genetic data into usable data, and then to analyze that data. That piece is where we come in, and are at the forefront of the field.

I used Lofta. They were much more interested in selling me their CPAP machines than explaining the results to me. (I was so borderline, CPAP would not be the first treatment anyone would recommend.)

Seems like the more companies like this with varying abilities of marketing to get as widespread outreach the better.

It seems you've made up your mind on what the narrative should be. So I'll just stop here for now.

I don't like the phrase too much but short answer is intellectual honesty. For example, understanding what went wrong that was probably because of your decisions versus the market, customers, external forces, etc.

There are far too many examples of founders succeeding with an idea after many people before them failed with same idea. I think any good investor is cognizant of this.

A 3rd party called Sherwood was brought on to wind down the company. This is common thing for a company to do when there are lots of assets to sell and loose ends to tie up. Everything from office furniture to domains to etc. They made all the decisions to sell what to who.

If anyone wants a startup idea, it's to make the inverse of Stripe Atlas. Closing down a company properly is a very long and complicated process.

Good news, since then I've found my caps locks key.

Ok sure but what was the implication you were trying to make?

$40m but who's counting :)

I've seen the $66m figure quoted a lot but not sure where it comes from.

This actually highlights a big problem we had - aligning expectations of what "clean" meant between a customer and cleaner. Everyone has a different definition!

It's true if you have a capital-intensive business, I will ask some of the toughest questions. I do this to figure out where you are in your journey of learning, not to find reasons to not accept you. In fact, we all take super-extra precaution to not over-learn from our own failures.

And to be clear, I've invested in plenty of startups with similar models. But I understand your perception of how things went.

It's because Ted is not a programmer himself.

Unless you just came up with the idea, it's useful to have talked to users already and/or have some data that the idea is good. Having revenue or being launched already is not a requirement.

oops, fixed. thx :)

Thanks, appreciate it. If this one goes well, we may do a traveling version.

Hi, this is Adora from Startup School. Happy to answer any questions.

It's not really affiliated with YC; I just happen to work there.

I met Ted while trying to find a copy of the book and when he told me he had a bunch in storage, I volunteered to help sell the rest. 100% sales go to him.

This edition is just a reprint of his first edition. Ted re-published it himself.

I haven't read the Microsoft edition yet but I know Ted hates what they did with his book.

:( This was intended to be a talk on a pretty specific topic for the Startup School course. Day-to-day operations for pre-product market fit CEOs. Hopefully, it was useful and interesting in this context! Happy to take suggestions on how I could have done the interview better.

Clickable link: https://www.electionday.org/

Instead via the old method of phone, they're texting about the bills instead. It seems that's what people are more responsive to today. All communication is private. It has nothing to do with social media.

I was the application reviewer and I look forward to feeling silly :) But really, one of the things I've been thinking about for a long time is how YC can help every startup in the world. We're still not there yet but this pushed us some steps closer.

Hi everyone, after all this, we believe the right thing to do is to accept everyone into Startup School, so we're going to find a way to make this work. More info here: https://news.ycombinator.com/item?id=17806459

That would be cool. Sounds like you could build a community around that.

I liked Sam's rubric of how to evaluate a startup to work at. Same one that investors use. You invest time for equity, they $ for equity, so makes sense.

You should be able to edit your profile and company details when you log in.

Still makes sense, and you'll be eligible as long as you complete the course. One of our goals for Startup School is to help founders beyond the Silicon Valley and US. Great entrepreneurs are everywhere.

Nope, we will accept solo founders.

That figure does not include audit.

Advisors use most of their time on this doing group office hours sessions. Last year each advisor had around 25-30 companies each, so we only needed 100 or so. They're all YC alum who love to pay it forward.

Anyone can audit the course. If you'd like to participate fully, it is an application process.

Yep. We've tailored the content to fit all sorts of sales models. There'll also be plenty of other founders with similarly long sales cycles to chat to / learn from within the Startup School community.