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_acme

561 karma · joined December 5, 2013

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_acme··on The Heroin Business Is Booming in America
Yes, lofentanil is slightly stronger.
_acme··on The Heroin Business Is Booming in America
What is it that you mean by a 'non-addictive' opioid? They're all roughly equivalent in their addictive potential. Even those that are used to treat addiction, such as buprenorphine, cause physical and mental dependence.
_acme··on There is little research into the long-term effects of using antidepressants
Lamictal carries the potential for severe side effects, much more so than SSRIs/SNRIs. Lamotrigine prescribing information has a black box warning about life-threatening skin reactions, including Stevens–Johnson syndrome, DRESS syndrome and toxic epidermal necrolysis.
_acme··on There is little research into the long-term effects of using antidepressants
Do you have a way of knowing whether the Lexapro was more effective than a placebo would have been?
_acme··on There is little research into the long-term effects of using antidepressants
Do you have any evidence for the efficacy of antidepressants that others, including their manufacturers, do not? In fact, SSRIs/SNRIs are not particularly effective -- at least no more effective than placebo.
_acme··on How ZIP codes nearly masked the lead problem in Flint (2016)
Isn't the primary idea of an unincorporated town that it doesn't 'exist' for purposes such as mail?
_acme··on Homebrew 1.2.0
There is, but that's a waste of my time, when we could all just use normal words.
_acme··on First introduction to LaTeX
Word itself provides a compare function that works very well, and there are alternative tools that also provide versioning functionality that can be combined with various document management tools, essentially providing GitHub for Word files (see, e.g., Interwoven iManage, etc.).
_acme··on First introduction to LaTeX
Word itself will diff Word documents beautifully, and there are alternative solutions as well (Workshare/DeltaView, Change-Pro, etc.) that are even more powerful.
_acme··on Juice may taste good, but unlike the fruit, it’s not healthy
I think your personal experience is called an anecdote, not data.
_acme··on Juice may taste good, but unlike the fruit, it’s not healthy
What is a frugivore?
_acme··on Juice may taste good, but unlike the fruit, it’s not healthy
Do you have a source for this insane claim?
_acme··on Juice may taste good, but unlike the fruit, it’s not healthy
Eating an orange involves a great deal of time and effort, and results in a lot of mess and stickiness.
_acme··on Juice may taste good, but unlike the fruit, it’s not healthy
And I generally think most vegetables taste terrible. What's the point of going on about personal preferences here?
_acme··on Why Deutsche Bundesbank had to promise to leave 1200 tons of gold in New York
When was the last time gold was used in dentistry?
_acme··on How the Airlines Became Cartels
None of this is accurate. Airlines reps have the same information as you get on the website, and airlines usually charge an extra fee for booking via phone.
_acme··on The Mac Pro Lives
What is it that sucks about Terminal.app that iTerm2 fixes?
_acme··on The Mac Pro Lives
Out of genuine curiosity, what are the ways it is superior?
_acme··on We Don’t Do Legacy (2012)
Do you have any support for these accusations? These are bold claims.
_acme··on We Don’t Do Legacy (2012)
Yale's law school doesn't have grades (neither does Harvard, anymore). How is that emphasizing competitiveness?
_acme··on Why Classroom Technology Is Costing More Than Its Worth (2016)
"it's worth" not "its worth": it's means "it is". At least try to get the title of an article correct.
_acme··on Canada to announce marijuana will be legal by July 1, 2018
Oxycodone is still professionally manufactured in predictable dose pills.
_acme··on Canada to announce marijuana will be legal by July 1, 2018
What is hard to hedge? If you have a large investment in corporations in the pot industry (although I would dispute your claim that there is a lot of institutional money in pot now), you could easily hedge against the fall of these corporations with CDS and other derivatives.
_acme··on Canada to announce marijuana will be legal by July 1, 2018
Is there any real, peer-reviewed evidence that marijuana has any positive medical effects -- i.e., that it can be used "medically" to treat any disease?
_acme··on Why drug prices in America are so high (2016)
Do you have support for the claim that US-developed drugs are generally available sooner in non-US markets? My understanding was that these drugs are generally available first in the US market, but that the developers may use FDA approval to help with EU approval, etc.
_acme··on Suicides in Rural America Increased More Than 40% in 16 Years
D.C. citizens may have more electoral college votes per capita than California, but D.C. residents have no representation in the U.S. Senate.
_acme··on Suicides in Rural America Increased More Than 40% in 16 Years
No, America was rural before rail and the highway systems, as was the rest of the world. America has gotten progressively less rural since its founding as fewer people have had to be directly engaged in farming.
_acme··on Suicides in Rural America Increased More Than 40% in 16 Years
Dartmouth is in New Hampshire, and neighboring VT has Middlebury, ME has Bowdoin, Bates and Colby and MA has Williams, all in rural environments.
_acme··on With a 10-day supply of opioids, 1 in 5 become long-term users
If you're taking 45mg of oxycodone an hour, you are definitely going to have discontinuation symptoms when you stop.
_acme··on Opaque drug pricing in the U.S.
Bad lawyers also don't kill people as frequently as bad doctors.
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