Zenzero

Any context in which it is being used as a scrubber would be one where the people designing it would 100% be aware of this.

At the time the estate tax is being considered isn't that usually down to a single surviving individual? I imagine it's uncommon for a couple to die at once to qualify for the 27m exemption.

> Is that giardiasis treatment, or just let's kill everything and hope for the best? Glad it worked out for him.

The second one.

There is probably a distinction to be made between

"here is the theoretical limit given adherence to modern recommendations on cardiovascular health, exercise, etc."

and

"you all didn't listen and got fat instead"

I have expertise in both. I think the difference is that when moving from the highly rigid world of medicine into tech, I expected the varied level of skill and knowledge that exists. It just throws you off seeing people in tech with no background in medicine talk about medicine like they know it.

Most of my closest friends are docs. A couple of times at a brewery I've had them read some braindead takes from here for laughs. The people here making wild comments on the architecture of o1 or whatever don't get the same reaction from the crowd.

> They love to misdiagnose hypothyroid or diabetes so they can begin destroying your endocrines

Im sorry but as a doctor this made me crack up. I don't know what it is about HN that makes people jump into every medical thread and say really absurd things. Skipping screening tests isn't one-upping your PCP. You just get to play harder with specialty when stuff starts to break. Good luck buddy.

Modern civilized countries pay for healthcare with taxes. That costs everyone more with his decisions.

Maybe not a diagnosis, but dependent on history if my patient is throwing repeatable >200 systolic that's probably not one I'm going to just sit on waiting for repeat measurements.

Doctors recognize that non-invasive BP measurement is an imperfect screening tool. Anybody worth their salt isn't getting worked up about these level of details, because it's largely a waste of time and effort. The solution to an error prone screening tool is not to repeatedly use the screening tool. You move on to more accurate and focused methods of testing.

> are the studies always really done with far more accurate blood pressure readings, where the patient sits still for 5 min beforehand, keeps their legs uncrossed, is totally free of stress and anxiety, didn't exercise beforehand, etc.?

In situations where blood pressure really matters, we aren't playing around with the cuff and hand positioning. The patient gets an art line.

You probably will not find a worthwhile project outside of your area of expertise. The market for "a guy who can code built a software for your industry" is pretty saturated now.

Unless you can split hairs on why specific products don't appeal to people in a given niche/industry, at the technical level that the users care about, you probably won't find much success.

In my personal experience I come from the medical side of things. The amount of garbage software written by people who know nothing about how we work is obnoxious. They all advertise themselves as the "next generation, streamlined, efficiency boosting" magic pill for us, but it's about as convincing as your 5 year old telling you they can do your taxes.

So my advice is find something to do in an area of expertise you already have.

If you do have a deep interest in this it would probably help to learn immunology on a more detailed level. My suspicion is that articles like the one you linked feel unsatisfactory because they say things like this

> But if our immunity is “restructured” in some way every few months, we would again expect all viral infections to peak at the same time

It is clear the author doesn't have a good understanding of basic immunology.

Much of the mystique falls away when you understand concepts such as adaptive immunity (how it develops and is retained), antigenic drift, environmental conditions (on the host) that improve transmission, etc.

As expected, instead of a cogent argument for why you believe what you do, you simply deliver a rambling stream of anger and emotion.

Fundamentally, COVID public health recommendations revolved around minimizing transmission and preservation of medical resources while awaiting development of treatment options. No amount of ranting about being forced to sit in your house, other people being mean to you, or political gamesmanship changes that. No amount of complaining about imperfect solutions like masking or distancing detract from the overall validity of why they were recommended.

As a doctor I have had to have this kind of talk with people over and over. The underlying biology cares zero for your schedule or convenience in life. Given how noncompliance is a constant problem on an individual healthcare level, it's not surprising that we ended up with millions of people just like you who can't follow simple instructions and formed communities in support of their collective failure to do so.

> we still absolutely ridicule people who’d believe in most of the nonsense so that keeps it down

I think that's a major source of the problem here in the US. We have gotten away from outright calling stupid people stupid. The morons spouting the conspiracy theories, the emotionally charged stories, and the anti-intellectual nonsense do not deserve time or consideration. Yet we continue to be sensitive to their screeching about censorship and bias. Let them screech all they want. Their opinions don't matter.

Exactly. It's maddening seeing all of these uneducated people spouting full throated delusions as fact and everyone else allows these people to have room to spread their nonsense.

Im frankly pretty shocked that HN, which usually has a relatively educated user base compared to most other sites, is allowing this kind of drivel from people who have no idea what they are talking about.

> We were all told to shut the fuck up and listen to a handful of cherry picked “doomsday experts”

No, you were told to out aside your opinions and allow people educated in epidemiology to guide a rapidly changing situation. It turns out the there were too many people with a chip on their shoulder to make the policy recommendations effective.

> if we were to express any doubt of any kind, we were evil alt-right grandma killers who deserved horrible Covid deaths.

Pointless hyperbole.

> no acknowledgment of the harms they were causing

Such as?

> What the Covid “side” did was abhorrent and history will not look fondly on them at all.

Reading between the lines it seems like you have many baked in assumptions that distort your perception of the event.

No I'm referring to how the chain of thought transcript seems like the output of two instances talking to each other.

To me it looks like they paired two instances of the model to feed off of each other's outputs with some sort of "contribute to reasoning out this problem" prompt. In the prior demos of 4o they did several similar demonstrations of that with audio.

I have a hard time believing that stereoscopic image analysis will ever surpass the efficiency of lidar map analysis of 3d spaces. Given how hard self driving is, it would make sense to make the ugliest, sensor-packed vehicle a working model, and then miniaturize /prune from there.

Starting with "basic" sensors is backwards. It is like aspiring to become a chess grandmaster so good you can play with your eyes closed, and starting out as a beginner with your eyes closed.

It only sounds like a silly statement because we kept the name "computer". In terms of what a computer was in 1943? He was probably right.

> You probably dont have enough context to have clarity here

I clearly didn't, so thank you for dropping by to enlighten me on it.

> We have spent our time on those code changes, leaving nearly zero time for public relations on this, but I hope to start changing that soon

Yes I can tell you at least from where I'm sitting it has felt that the other frameworks have had online presence/excitement, whereas Express has (perhaps wrongly) felt absent. I'm glad to hear you're jumping back into the mix.

> humans manage with just vision.

But they don't. I can't see how anyone could look at modern driving and see an optimal state. Driving isn't being managed at all, it's killing droves of humans.

If we put the same restrictions on airplanes (flying by instrument is a crutch), everyone would rightfully find that ridiculous.

They appear to have bet on the wrong technology. The failure happened back in the design phase.

The halo effect in action.

Like many things in life, "it's close" is not worth celebrating, especially if it's not clear how the gap will be solved.

I'm no expert, but anyone can look at the sensors placed on a Waymo compared to a Tesla and likely rightly assume Waymo doesn't have all of that extra stuff just for looks.

I don't see how Tesla is even a serious contender.

Given how this has been 10 years in the making, I really wonder if this sends a message to the wider community to consider the alternatives like Hono, Elysia, etc. It just looks like this update doesn't speak to the main reasons why people are switching (performance, simplicity).

I wouldn't expect Express to dump Nodejs, but at least attempt to stay competitive.

I know Express will remain in existing projects for decades to come, but it would give me pause when considering what to use for any greenfield project.

Feels more similar to getting cut by a kitchen knife. I would not recommend it.

There's nothing stopping anyone here from coming to your public website and downloading your images for use in a training set. If someone did that, why would they be posting online where they pulled data from?

Not going to lie, I think Bluesky's effort is good for reducing inflammatory and combative behavior on the internet. So this response:

> This is a terrible idea

Got a good chuckle from me.

You misunderstand the concept of a placebo.