Rewrap3643

I use Rectangle for this purpose.

Psychs won't prescribe it because it's a wakefulness promoting agent, not a typical stimulant. There's insufficient evidence to prescribe it as a first-line treatment for ADHD. Insurance companies are also unlikely to pay for it in absence of a diagnosed sleep disorder.

Methylphenidate is the clinically correct alternative to amphetamines.

This has no bearing in reality. Furthermore, the others in this thread are referring to therapeutic doses of amphetamine, not microdosing literally.

The level of nonsense perpetuated on that site based on rat studies is absurd.

Furthermore it's a reactive measure. Locking credit reports and unlocking as needed can help mitigate some risks.

Have you done a color blindness test before? Red-green is the most common type and the differences here are mostly shades of green.

Sleep apnea is not exclusively a lifestyle disorder. I have it with a BMI of under 21.

NextDNS works fine for me.

The metabolite of nicotine has a long half-life and probably degrades sleep quality.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443078/

Are you familiar with Kagi Lenses?

https://help.kagi.com/kagi/features/lenses.html

Not really. Your best bet is to buy them from a vendor who does batch testing (as opposed to lot testing) and will present you with a lab’s certificate of analysis when requested.

This is a case report of an individual that experienced lead poisoning from Ayurvedic supplements. It is from Canada’s public health system.

One of the linked studies which analyzed 193 supplements found that 39 of them were contaminated. That was funded in part by the US NIH, hospitals, and universities.

The only thing I can see that’s suspicious are the people pushing these harmful products.

The negative health effects of junk food are largely reversible, unlike lead poisoning.

Correct, which is why the warrant was limited to computers in the United States (I don't know how they went about this in practice).

https://www.justice.gov/d9/2023-08/23mj4244_warrant_redacted...

Trazodone should not be compared with those other drugs. It is hardly anticholinergic, and it lacks many of the side effects of Seroquel or Ambien. It can actually improve sleep architecture; it acts as a slow-wave sleep enhancer. In addition, it may increase the "arousal threshold" in certain patients with sleep apnea. This translates into less disruptions to sleep overall. [1][2]

Comparing this to something like Ambien- which disrupts sleep cycles and correlates with increased mortality overall- just isn't factual. [3]

Anecdotally, a low dose of trazodone (25 mg) prevents sleep maintenance insomnia for me. You should definitely have a sleep study done regardless. Wishing you some restful sleep!

[1] https://pubmed.ncbi.nlm.nih.gov/30689583/

[2] https://pubmed.ncbi.nlm.nih.gov/25719754/

[3] https://pubmed.ncbi.nlm.nih.gov/30353805/

You have to trust OpenAI follows their privacy policy. Otherwise, you shouldn't use their service.

'When you use our non-API consumer services ChatGPT or DALL-E, we may use the data you provide us to improve our models. You can switch off training in ChatGPT settings (under Data Controls) to turn off training for any conversations created while training is disabled or you can submit this form. Once you opt out, new conversations will not be used to train our models.'[0]

'When you use our Services, we collect Personal Information that is included in the input, file uploads, or feedback that you provide to our Services (“Content”).

...

We may automatically collect information about your use of the Services, such as the types of content that you view or engage with, the features you use and the actions you take, as well as your time zone, country, the dates and times of access, user agent and version, type of computer or mobile device, and your computer connection.'[1]

[0] https://help.openai.com/en/articles/5722486-how-your-data-is... [1] https://openai.com/policies/privacy-policy

What would you propose then?

I don't think we know enough about it, other than to say, "sleep is important and disrupting it should be minimized."

There's a medication called trazodone which is used off-label for people with issues falling or staying asleep. It increases the total percentage of time spent in slow-wave sleep (stage 3).

Even though this comes at the expense of REM, in elderly people with cognitive or neurodegenerative issues, this appears to confer a protective benefit (the rate of deterioration is slowed comparatively).

That said, it would probably be ideal if they slept well without medication and altered sleep architectures.

Body temperature can influence sleep significantly. You’re probably warmer when co-sleeping.

Meth is significantly different than regular amphetamine. Consider that simple changes in isomers can elicit radically different effects. A great example is levmetamfetamine (or l-meth), which is sold over the counter as a decongestant (as opposed to d-meth, the “fun” kind).

Now, if the difference between a “left-handed” and “right-handed” meth molecule can be so great, it shouldn’t come as a surprise that adding a methyl group to regular amphetamine will change its effects considerably.

This can be seen in the different receptor binding profiles (which receptors, where in the brain, and how strong or long the modulation is).

Meth’s increased addictive and neurotoxic effects are owed to this difference in receptor binding.