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John7878781

200 karma · joined January 29, 2025

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John7878781··on Gemini 3.5: frontier intelligence with action
[deleted]
John7878781··on FDA approves first gene therapy for treatment of genetic hearing loss
Do you worry about having an increased risk of Alzheimers/Dementia?
John7878781··on FDA approves first gene therapy for treatment of genetic hearing loss
Why are you so hostile?
John7878781··on UK Biobank health data keeps ending up on GitHub
What are the pros/cons of just open-sourcing everything for future bio bank projects?
John7878781··on Landmark ancient-genome study shows surprise acceleration of human evolution
> Two bird populations living in the same locale but divided by a mountain range therefore not naturally breeding with each other would classify as a different species, even if they could breed with each other.

Really? I thought the requirements for species classification were: (1) must be able to reproduce and (2) offspring must be fertile.

Is it less objective than that?

John7878781··on AI Will Be Met with Violence, and Nothing Good Will Come of It
> it just a statistical model, text-in, text-out (and it humans that feed the input and act on the output).

You're not thinking long-term. What happens when AI is put in charge of systems that interact with the physical world?

John7878781··on Surely the crash of the US economy has to be soon
Is it just me or does this metaphor sound AI generated?

> It is like a memory leak that keeps sucking resources while growing exponentially until the system crashes. The real question for an economist is how much ram has the system and how much the memory has leaked?

John7878781··on [dead]
https://archive.is/352Jo
John7878781··on ChatGPT is getting ads. Sam Altman once called them a 'last resort.'
I like the video recommendations.
John7878781··on Cloudflare acquires Astro
Is it just me or is this entire comment AI-generated?
John7878781··on A Mystery Trader Made $400k Betting on Maduro's Downfall
It is well documented that Trump engages (directly or indirectly) in insider trading.

https://blogs.law.ox.ac.uk/oblb/blog-post/2025/04/most-far-r... https://www.propublica.org/article/us-officials-stock-sales-... https://www.theguardian.com/business/2025/dec/10/trump-donor...

John7878781··on MHRA approves self replicating mRNA Covid-19 vaccine
I am by no means dismissing this achievement. But can anyone explain to me the advantages of this over the current COVID vaccines? Is it more effective?
John7878781··on UN Says US Raid on Venezuela Violated International Law
How shocking!
John7878781··on Ripple, a puzzle game about 2nd and 3rd order effects
I wonder if this could be used to gauge someone's optimism/pessimism.
John7878781··on Anti-aging injection regrows knee cartilage and prevents arthritis
In some contexts (e.g., pancreas), 15-PGDH inhibition can promote tumor growth by increasing specific signaling.
John7878781··on Researchers develop a camera that can focus on different distances at once
It's not even loading for me (probably because it's a huge file).
John7878781··on NYC Spends $200 Million on Cell Service for School Chromebooks
> What is the reason given for Chromebooks being used so much in US schools?

Chromebooks are much cheaper than Windows laptops.

Similarly priced chromebooks are also much more responsive than their Windows counterparts (mainly due to the OS being so optimized to run on crappy hardware). And you're right -- Linux might be a viable alternative here. But it's not like the corporate world runs on Linux.

John7878781··on What is the nicest thing a stranger has ever done for you?
Reading all the other comments really puts a smile to my face (as cliche as that sounds).
John7878781··on Over fifty new hallucinations in ICLR 2026 submissions
Yep. And trust is already at all time lows for science, as if it couldn't get any worse.
John7878781··on The effect of shingles vaccination at different stages of dementia
> But the first clinical trial to test that theory has found that a common antiviral for herpes simplex infections, valacyclovir, does not change the course of the disease for patients in the early stages of Alzheimer's.

https://www.cuimc.columbia.edu/news/antiviral-treatment-fail...

John7878781··on Stackoverflow Outage
While LLMs may have used Stack Overflow data to get their start, I think it's reasonable to assume that this source of training data will no longer continue to be useful.

Therefore, as both a data source and a QA website, Stack Overflow has lost its relevance.

John7878781··on Stackoverflow Outage
Stack Overflow is no longer relevant. Today, you can just ask Gemini, Claude, or ChatGPT instead, and you don’t have to deal with the usual condescension.
John7878781··on Show HN: Nano PDF – A CLI Tool to Edit PDFs with Gemini's Nano Banana
Love this.

After several iterations of edits, would the image quality decrease?

John7878781··on Yann LeCun to depart Meta and launch AI startup focused on 'world models'
Gemini 2.5 Pro works great for me... In fact, I would go as far to say that it consistently performs the best compared to competition.
John7878781··on Yann LeCun to depart Meta and launch AI startup focused on 'world models'
Is he wrong though? Do you really think LLMs are the path to AGI?
John7878781··on Gemini 2.5 Computer Use model
That doesn't matter so much when it can happen in the background.
John7878781··on Microsoft is about to launch free Xbox Cloud Gaming with ads
People are going to inevitably hate on this because... well it's ads.

But in my opinion, having an ad-supported tier is actually a good thing. It makes gaming more accessible to people who can't afford/don't want to purchase expensive gaming PCs.

Plus, it adds competition with nvidia's geforce streaming service (which is already ad-supported).

John7878781··on Small Objects, Big Gains: Benchmarking Tigris Against AWS S3 and Cloudflare R2
Agree. There are literally zero takeaways from this article other than it being a marketing post.
John7878781··on Show HN: Use Their ID – Use your local UK MP’s ID for the Online Safety Act
It's better to be safe than sorry. For your own best interest, I would shut down the site and delete this post.
John7878781··on Android Earthquake Alerts: A global system for early warning
Doesn't seem that obvious to me
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