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462436347

417 karma · joined July 23, 2022

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462436347··on Chinese migrants are fastest growing group crossing into U.S. from Mexico [video]
At 5:45 they show how the migrants are given step-by-step instructions on how to sneak in by TikTok videos.
462436347··on New IBM LinuxONE 4 Express – Rack-mounted pre-configured Linux mainframe
The linked page doesn't once contain the word mainframe.
462436347··on Lost "Doctor Who" episodes found but owner is reluctant to hand them to BBC
Most countries in Europe and Latin America: https://en.wikipedia.org/wiki/Inquisitorial_system
462436347··on Lost "Doctor Who" episodes found but owner is reluctant to hand them to BBC
> These collectors were seen as criminals, but now we can see they are really saviours. An amnesty would stop them being frightened of prosecution,” he said.

The UK is unusual in that it has no statute of limitations for most crimes besides "summary offenses" (equivalent to US misdemeanors): https://en.wikipedia.org/wiki/Limitation_periods_in_the_Unit...

462436347··on U.S. Sugar consumption trend from 1970-2021
> This is not relevant to arguments (with sources and statistics) about systemic obesity he presents.

Yes it absolutely is, since he claims he doesn't eat sugar for all the reasons he cites, yet he's fat and looks metabolically unhealthy:

https://www.wnycstudios.org/podcasts/heresthething/episodes/...

>Robert Lustig: I carry a few extra pounds and I’m not happy about it. I don’t eat sugar.

>Alec Baldwin: You don’t.

>Robert Lustig: No. I have dessert twice a year. When I’m in New York I have a piece of Junior’s cheesecake and when I’m in New Orleans I have bread pudding -

Notice his twice yearly dessert sugar indulgences are high in fat.

> If dietary fat is more easily stored as fat,

You seriously believe your body preferentially uses de novo lipogenesis to convert carbohydrate to fat (which entails some energy loss) rather than just storing fat as fat? DNL on a typical mixed macro diet is rare, to the point that something like 90% of your bodyfat came from fat you ate, and the fatty acid profile of your body mirrors that of your diet: https://pubmed.ncbi.nlm.nih.gov/12324287/

Even in low-carb circles, this is tacitly acknowledged now by warning against eating meat from animals fed a high-PUFA diet, like poultry.

I'm not saying overeating carbs won't make you fat, but arguing that it somehow makes you fatter, calorie-for-calorie, than fat is ridiculous considering that eventually your body runs out of fat and has to use DNL (which is inefficient), and that fats require the least energy for your body to digest of any macro.

> why do keto diets work?

They don't, at least not any better than low-fat diets. They seem to work better initially because keto dieters lose a lot more weight early, but that weight is disproportionately fat-free mass, i.e., water, glycogen, and probably at least some lean body mass (muscle and bone density). See the graph on p. 4 of Kevin Hall's NIH study comparing the diets:

https://sci-hub.se/10.1038/s41591-020-01209-1

462436347··on U.S. Sugar consumption trend from 1970-2021
He posted, then deleted, a response saying he's not diabetic, but isn't healthy either. I guess he wears a CGM because he falsely believes transient blood glucose spikes ultimately cause T2D.
462436347··on U.S. Sugar consumption trend from 1970-2021
The straw-graping replies to this thread are pretty funny. It's somehow still all sugar's fault, because it just is, with at least one repost of Dr. Lustig's viral Sugar, The Bitter Truth lecture from 12 years ago (when people ironically ate more sugar and weren't as fat or obese as they are today), and a neurotic low-carber who wears a CGM despite not being diabetic (and not knowing that dietary fat intake is actually a stronger risk factor for T2D than sugar).

>I wish we could get a graph of fat intake of the last hundred years.

See: https://news.ycombinator.com/item?id=38094902

462436347··on U.S. Sugar consumption trend from 1970-2021
> and is more easily stored as fat

Dietary fat is even more easily stored as fat, since it doesn't require the added step of de novo lipogenesis (DNL) like carbohydrate does, or the added steps of gluconeogenesis + DNL as protein does. And go look up recent photos of Lustig: he's fat (bordering on obese) himself.

462436347··on U.S. Sugar consumption trend from 1970-2021
> Fat is estrogenic

I meant bodyfat specifically

462436347··on U.S. Sugar consumption trend from 1970-2021
> It's addictive because there's very little of it in nature and it's high energy density

Fat has 2.25x times the energy per gram that sugar does.

462436347··on U.S. Sugar consumption trend from 1970-2021
> You can learn a lot wearing CGM

Are you diabetic?

462436347··on U.S. Sugar consumption trend from 1970-2021
> There's a very good reason why sugar is so "addictive"

Sugar on its own isn't addictive and isn't a necessary nor sufficient ingredient for hyperpalatability. Foods can be hyperpalatable without sugar, and in fact most (~70%) hyperpalatable foods have their hyperpalatability driven by fat and sodium:

> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9672140/

> The availability of HPF in the US food sysltem has expanded substantially over the past 30 years. The current US food supply is highly saturated with HPF, which our findings indicate comprised almost 70 % of available foods as of 2018. The growing availability of HPF over time, particularly HPF high in fat and Na, may have resulted from the reformulation of existing food products in the food system to be hyper-palatable. Thus, expanding HPF availability may be one key contributor to the obesogenic food environment in the US. Given potential consequences for population health, policy-level action is needed to address the presence of HPF in the food system. Policy may focus on limiting the nutrient thresholds allowed in foods to be below HPF thresholds (e.g. foods should contain <25 % kcal from fat and <0·30 % g from Na).

462436347··on U.S. Sugar consumption trend from 1970-2021
> You can note that average male height in the US continued increasing up until the late 1980s.

Fat is estrogenic, and estrogen accelerates growth plate fusion.

462436347··on U.S. Sugar consumption trend from 1970-2021
The point is the added calories aren't coming from sugar, contrary to what everyone here thinks. And even if sugar did somehow magically make you fat regardless of calories, sugar consumption has actually gone down, yet the obesity and diabetes epidemics have only gotten worse.
462436347··on U.S. Sugar consumption trend from 1970-2021
It's probably multifactoral. For example, here's a recent provocative paper from a highly respected researcher (John Speakman) arguing metabolic rates have actually slowed since then: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445668/

But two decades of "fat doesn't make you fat" probably didn't help, and neither did the continued trend of increasing empty calories from cheap vegetable oils, especially soybean oil: https://thedietwars.com/why-are-americans-getting-fatter-a-f...

https://www.ers.usda.gov/webdocs/charts/59529/indicators_goa...

>Added fats and oils provide more calories per day for the average American than any other food group

EDIT: I think most Americans would be shocked to discover that their "favorite" food group is added fat/oil.

462436347··on U.S. Sugar consumption trend from 1970-2021
Alternate title: the graph that broke HN's brain. You'll notice that 1) sugar consumption peaked around Y2K and declined after 2) the decline was driven by a decline in consumption of High-Fructose Corn Syrup (the most vilified sugar) specifically, and 3) the average American now consumes about as much added sugar as the average American did in 1970--yet their waistlines are not remotely comparable.

Technically the graph is of per capita added sugar availability and isn't adjusted for loss (due to spoilage, plate waste, etc.), but it meshes with NHANES survey data: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434277/

>In conclusion, over the 18 year time span, from 2001 to 2018, added sugars intake declined significantly among younger adults (19–50 years) in the U.S., regardless of race and ethnicity (i.e., similar for Black and White individuals), income level, physical activity level or body weight status, and declines were mainly due to reductions in added sugars intake from sweetened beverages (primarily soft drinks and fruit drinks). These trends coincide with the evolving emphasis in the DGA on reducing added sugars intake and the increasing focus on population-level interventions aimed at reducing intakes.

462436347··on Tech executive Bob Lee led an underground life
> He was a good guy, didn't hurt anyone, and was senselessly murdered in cold blood.

He had an affair with a married woman and spent his free time attending sex- and drug-fueled parties instead of at home with his two kids and wife. Yeah, he didn't deserve to die, but saying "he didn't hurt anyone" and was "senselessly" (as in, for absolutely no reason) murdered is a ridiculous take. Go read the comments on the Post article I linked to, and see what normal people (as in, not in the SV/VC ecochamber) think about all of this. Spoiler: largely unsympathetic to what they perceive as a rich, hedonistic "techbro" who met an untimely end.

462436347··on Tech executive Bob Lee led an underground life
https://nypost.com/2023/05/14/cash-app-founder-bob-lee-atten...

>Known in wealthy circles as “The Lifestyle,” Lee, 43,a father of two, allegedly enjoyed the city’s underground party scene, as did Khazar Momeni, wife of a prominent plastic surgeon and sister of Nima Momeni.

>People familiar with the group said Lee and Khazar, 37, were sleeping together, and many feared he’d fallen into a dangerous lifestyle, surrounding himself with the wrong group of people.

>Lee was allegedly confronted by Nima about the hard-partying and his sister’s involvement in an argument erupting in the early hours of April 4 when Lee was stabbed multiple times, prosecutors said.

"The Lifestyle" refers to the scene to which he belonged, not the man himself, btw (at least according to another article).

462436347··on NIH restarts bat virus grant
I can't for the life of me understand the personality cult of Sam Altman. He gives off sociopathic vibes, and looks (probably thanks to plastic surgery) creepy.
462436347··on Freud as Talmudist
I'm flagged too. Unbelievable that criticism of Sigmund Freud is controversial on HN, a site overrun with "IFLS" types.
462436347··on Freud as Talmudist
> Skinner was a charlatan for behaviorism

Being wrong doesn't make you a charlatan. Skinner, to his credit, tried to operate scientifically, by formulating empirically falsifiable hypotheses and testing them. Freud, by contrast, crafted reams of "theory" that his followers were expected to unquestioningly accept as gospel.

462436347··on Freud as Talmudist
> As somebody with a jacked up spine, chiropractic care has its place

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016850/

462436347··on Freud as Talmudist
> Lysenko

You're sympathetically comparing him to Lysenko, which only proves my point: both were unscientific charlatans legitimized by leftists, to the detriment of many.

462436347··on Freud as Talmudist
> where Freud never even was mentioned

Maybe he wasn't mentioned by name, but he was a major influence on earlier versions:

https://psychmuseum.uwgb.org/clinical/dsm

462436347··on Freud as Talmudist
> Why are there so many psychologists practicing psychoanalysis today, then?

There aren't. Psychology (in the US) abandoned Freud roughly in the 50s and 60s, with the rise of Behaviorism and later Cognitive psychology. These movements tried to make psychology an empirical science, with testable hypotheses subjected to replicable experiments. (Obviously, given the replication crisis, this effort hasn't been completely successful.) Psychiatry (the medical specialization) took much longer, until the 80s, but eventually they dispensed with his nonsense as well.

Most talk therapy today entails some form of CBT, REBT, ACT, or something similar, and these have nothing to do with Freud.

462436347··on US could soon approve MDMA therapy
Comparing it to chemotherapy doesn't really undermine my point, does it? And the ultimate goal of the proponents is not just to get these drugs made available via prescription, but to make them as legal as marijuana.
462436347··on US could soon approve MDMA therapy
> Please read the original Phase III and earlier studies where they thoroughly address these questions under the treatment modalities being tested.

The problem is these drugs aren't being presented as dangerous pharmaceuticals that still have worthwhile cost-benefit ratios for certain serious conditions. Instead the "drugs are good" crowd actually argues, laughably, that they're completely safe, and safer than alcohol (I don't drink, btw), despite extremely good observational data suggesting moderate drinking doesn't increase all-cause mortality, while no similar data at present exists for these drugs.

Here's an example of something they never discuss: https://slatestarcodex.com/2018/06/06/hppd-and-the-specter-o...

The "microdosing" fad is one of the best examples of how uninformed people are about the dangers of psychedelics, thanks to the propaganda. If I polled 100 of these microdosers at random and asked them about 5HT2B, do you honestly think more than half would know what I was talking about, and what my concerns are? Yeah, some are highly informed and know what risks they're taking, but they're the exception.

462436347··on US could soon approve MDMA therapy
Almost 350 comments, none of which mention how dangerous MDMA is, especially to the kidneys, the heart, and the serotonergic neurons of the brain?
462436347··on Cash App founder stabbed after allegedly drinking with suspect's sister
Do a lot of fundamentalist Muslims live in SF?
462436347··on Sam Altman is a doomsday prepper with a stash of gold, guns, and gas masks
The gun part is pretty hypocritical though, isn't it? The guy at least pretends to be a Democrat, and donates to Democratic PACs, which support gun control, meanwhile he's stocking up on guns and ammo himself: https://www.forbes.com/sites/michelatindera/2020/05/22/silic...

Maybe he just doesn't want the masses/little people/useless eaters owning firearms?

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