And yes, the priors - like the probability that a 20 year old female college student with no history of violence or mental disturbance of any kind would commit a murder - are certainly very relevant. That is one of the least violent categorizations of humans you can create. (In fact a more accurate prior would be even more miniscule: the probability that such a person would lead an elaborate team sex murder, an act so rare there is no term for it.)
(However, there is some other evidence that is hard to deal with in this model, like the crime lab saying that there is Knox DNA on the bloody bra clasp of the victim. That evidence seems hopelessly entangled with the murder. How can this model be used to reason about it?)
Anyway, all I know of the case is what other commenters here and the OP on lesswrong.com wrote, so my facts are suspect. I've just tried to explain what the OP is saying. Did I succeed?