1. Does it have active plate tectonics?
2. Does it have a working deep carbon cycle?
3. Has its atmosphere hung on to its hydrogen (that is, has it managed not to lose it all to high-altitude UV splitting and solar wind)?
If the answer to all three of those is "yes" then this suddenly gets a lot more interesting, whether or not we can see any free oxygen in the atmosphere. And while we won't be able to get answers to them using current technology, next-generation direct-observation planet seeking telescopes might be able to deliver within the 15-30 year time scale (if the astrophysicists I know are correct).