A script that automatically submits to virustotal is like reinventing a very slow virus scanner.
* I think virustotal could be easily monetized (without altering or cheapening itself) by freemium to orgs, nonprofits, govts that want faster, private, shared/dedicated access to the same "cloud" capabilities. There was HitmanPro which was good early on, but it didn't seem to be stay anywhere near as comprehensive as virustotal.