Interesting awful business model idea: make lots of bots to click around flight reservation sites and hold seats to drive the prices for those seats up, then sell the seats your bots are holding for more than they're paying and less than the now-inflated price available to everyone else. I'm sure there's a name for this, not sure if it's legal.
EDIT: bonus round: screw with airline algorithmic pricing algorithms so hard that all their models get so screwed up that they end up ditching the idea. Victory for everyone except the airlines. Use the arbitrage profits to push this agenda. I'm sure you'd get sued out of existence long before it ever worked (unless e.g. It's open-source and ran by individuals), but it'd be hilarious. This is the kind of stuff I'd fund if I were rich.