Conversely: I use ^S and ^Q _all the time_. I've got a long-running program that's spewing output to a terminal? ^S and it stops so I can look at it, copy output elsewhere, etc. ^Q and it resumes again seamlessly.
It occurs to me that I grew up on the BBC Micro, where pressing Ctrl+Shift would pausing scrolling, so being able to do this is tightly engrained in muscle memory...