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Yes, you can just configure the spdy plugin for nginx and place it in front of your webserver. Easy and we measured significant load-time wins.

This might be too much to ask, but you can share the Nginx config file(s)?

Adding SPDY is really nothing much in nginx (and that one of the thing that makes it awesome).

In practice, if you already have an SSL server, just add the "spdy" to the listen line like "listen 443 ssl spdy;", restart and you are done[1].

Then making it proxy request is just one location definition with "proxy_pass"[2].