Last time I made a presentation with slides was some 15 years ago. I used SliTeX. (It seems that has been superseded by a slides document class in LaTeX2e.)
The slides were very plain: just black text on a white background; no animations. On the other hand, great looking formulas, nicely formatted source code snippets and such.
I had a talk prepared; it wasn't a slide-reading marathon. The slides just anchored what I was saying.
Today if I did slides, I would probably make them into static HTML pages with simple navigation links. Or perhaps a dual frame: navigation pane with screens.